Protein
Membrane protein RL13
Organism
Human cytomegalovirus (strain Merlin)
Function
May play a role in modifying tropism or in modulating cell signaling during virus entry. Since RL13 expression severely impairs HCMV replication in epithelial cell cultures, it may act as a regulator promoting persistence by suppressing the switch to fully lytic infection.
Sequence
MHWHLAITWTVIILTFSECYNQTCPCPCICVNSTTVSISTSETTSKNITPTTTTNSKKTTSSIATTTPSLVTTGKVVSTAASSTIISQTNRSHTSNAITTPKTRFEYNITGYVGQEVTLNFTGSWNYIQWFRYGSPGWLYSSEPICTVTSNYHHTFPRGALCFDCDMTKLLIYDLTLNDSGKYVVKRTRHDNQYEEACYSLTVIFANTTSIVTNRTCDRKRTENTDTTNHEIGKHIIETIKKANIPLGIHAVWAGIVVSVALIALYMGNRRRPRKPRYTRLPKYDPDESWTKT