About Products Protein Database Contact

RIMBP3

Gene
RIMBP3
Protein
RIMS-binding protein 3A
Organism
Homo sapiens
Length
1639 amino acids
Function
Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development.
Similarity
Belongs to the RIMBP family.
Mass
180.717 kDa
Sequence
MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQAENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARKLQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGAQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELEDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGVVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRARVEVRLPRDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTLLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCSQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLWGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGNLPSVAHLEDFQGLTIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH

Gene
Rimbp3
Protein
RIMS-binding protein 3
Organism
Mus musculus
Length
1606 amino acids
Function
Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development (PubMed:19091768, PubMed:28003339). Important for male fertility (PubMed:19091768).
Similarity
Belongs to the RIMBP family.
Mass
177.278 kDa
Sequence
MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHSPNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTSSPQPPPQLPSIHRKPNDLQKESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSETSETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNPFPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDGTNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEEKEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKRECSVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGSYMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE