RIMBP3

Gene

RIMBP3

Protein

RIMS-binding protein 3A

Organism

Homo sapiens

Length

1639 amino acids

Function

Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development.

Similarity

Belongs to the RIMBP family.

Mass

180.717 kDa

Sequence

MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQAENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARKLQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGAQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELEDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGVVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRARVEVRLPRDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTLLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCSQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLWGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGNLPSVAHLEDFQGLTIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH

Protein

RIMS-binding protein 3A: RIMBP3

Gene

Rimbp3

Protein

RIMS-binding protein 3

Organism

Mus musculus

Length

1606 amino acids

Function

Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development (PubMed:19091768, PubMed:28003339). Important for male fertility (PubMed:19091768).

Similarity

Belongs to the RIMBP family.

Mass

177.278 kDa

Sequence

MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHSPNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTSSPQPPPQLPSIHRKPNDLQKESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSETSETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNPFPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDGTNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEEKEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKRECSVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGSYMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE

Protein

RIMS-binding protein 3: Rimbp3