RIB1

Gene

RIB1

Protein

GTP cyclohydrolase-2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

345 amino acids

Function

Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

Similarity

Belongs to the GTP cyclohydrolase II family.

Mass

38.332 kDa

Sequence

MTIDNYDNSKQDSSKYEVSGTGDGRNGDGGLPLVQCVARARIPTTQGPDIFLHLYSNNRDNKEHLAIVFGEDIRSRSLFRRRQCETQQDRMIRGAYIGKLYPGRTVADEDDRLGLALEFDDSTGELLASKATTWDAHNDTLVRIHSECYTGENAWSARCDCGEQFDRAGRLIACDHEPTSNIKGGNGHGVIVYLRQEGRGIGLGEKLKAYNLQDLGADTVQANLMLKHPVDARDFSLGKAILLDLGIGNVRLLTNNPEKIKQVDHAPYLKCVERVPMVPIHWTNSSEGIDSKEIEGYLRTKIERMGHLLTEPLKLHTNPQPTETSEAQNQNRMNSALSSTSTLAI

Protein

GTP cyclohydrolase-2: RIB1

Gene

RIB1

Protein

GTP cyclohydrolase-2

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)

Length

332 amino acids

Function

Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

Similarity

Belongs to the GTP cyclohydrolase II family.

Mass

37.147 kDa

Sequence

MASKDIVHPQPERRHGSETHEFTMPLLSPTLTPSHIPSQTPQIPPEVPAEVRDRLPLPETLPVVKCMARARIPTTQGPEIFLHLYENNVDNKEHLAIVFGEDVRSKTLYQKRPNETQQDRMTRGAYVGRLFPGRTEADYDSESNLRLNFDENGQLIRDPSTTCSGEPILARIHSECYTGETAWSARCDCGEQFDEAGRLMGEAGHGCIVYLRQEGRGIGLGEKLKAYNLQDLGADTVQANLMLRHPADARSFSLATAILLDLGLNEIKLLTNNPDKIAAVEGRNREVKVVERVPMVPLAWRSENGIKSKEIEGYLSAKIERMGHLLEKPLKI

Protein

GTP cyclohydrolase-2: RIB1

Gene

rib1

Protein

Probable GTP cyclohydrolase-2

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

326 amino acids

Similarity

Belongs to the GTP cyclohydrolase II family.

Mass

36.524 kDa

Sequence

MDKKEGDQVHHDKTLLQDLSLPENVASEKRLPIDDVQCVNSPMLSPALDIEPKPNVVGTAERLPKVRCVVRARIPTVKGTEIFLHLYKNDFDNKEHLAIVFGQQIRSDSLDAVQEGETEMDRMVRGAYVGTLYPGRKSSYIDVNSSKTTEEQKEEARKTNFVPLVRIHSECYTGETAWSARCDCGEQLDEAARLISEEGNGVIIYLRQEGRGIGLSEKLKAYNLQDLGNDTVQANLLLQHPADGRSYAVATAMLMDLGQRDIRLLTNNPEKVNSIEGPNKEVRVVERISMIPKSWRGEKGIESAEVVLYLKTKIEKMGHLLDLPDS

Protein

Probable GTP cyclohydrolase-2: rib1