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RHBDL2

Gene
RHBDL2
Protein
Rhomboid-related protein 2
Organism
Homo sapiens
Length
303 amino acids
Function
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
Similarity
Belongs to the peptidase S54 family.
Mass
34.021 kDa
Sequence
MAAVHDLEMESMNLNMGREMKEELEEEEKMREDGGGKDRAKSKKVHRIVSKWMLPEKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVWKPQKQWITLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN

Gene
Rhbdl2
Protein
Rhomboid-related protein 2
Organism
Mus musculus
Length
302 amino acids
Function
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3 (By similarity).
Similarity
Belongs to the peptidase S54 family.
Mass
33.735 kDa
Sequence
MAVAHEMEMESVNLNMEREGKEEPEEEKMKGNGEGKDFPRSRKVHRIVSKWMLPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVWKPQKQWITLDTGILESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN