RHBDF2

Inactive rhomboid protein 2

856 amino acids

Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

Belongs to the peptidase S54 family.

96.686 kDa

MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPEGFQNRRLKKSQPRTWAAHTTACPPSFLPKRKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRRKRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH

RHBDF2

Inactive rhomboid protein 2

827 amino acids

Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

Belongs to the peptidase S54 family.

93.61 kDa

MDSTDKNGESVSSVSSSRLQSRKPPNLSITIPPPEASAPGEQASMLPQRPRNPAYMKSVSLQEQRGRWQEGSSEKRPGFRRQASLSQSIRKGTAQWFGVSGDWEAKRQHWQRRSLHHCSVRYGRLKASCQRDLELPSQEVPSFQGTESPKPCKMPKIVDPLARGRAFRHPDEVDRPHAPHPPLTPGVLSLTSFTSVRSGHSHLPRRKRMSVAHMSFQAAAALLKGRSVLDATGQRCRVVKRSFAYPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPRSASPVSPDGVQIPLKEYGRPPVAGTRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHIIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWIGPSSIDLIHLGAKFSPCIRKDQQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQAKSNRTGFLHMDCQIKGRPCCISTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLVFAGLFASLVIWLYVYPINWPWIEYLTCFPFTSRFCEKYELDQVLH

Rhbdf2

Inactive rhomboid protein 2

827 amino acids

Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

Belongs to the peptidase S54 family.

93.434 kDa

MASADKNGSNLPSVSGSRLQSRKPPNLSITIPPPESQAPGEQDSMLPERRKNPAYLKSVSLQEPRGRWQEGAEKRPGFRRQASLSQSIRKSTAQWFGVSGDWEGKRQNWHRRSLHHCSVHYGRLKASCQRELELPSQEVPSFQGTESPKPCKMPKIVDPLARGRAFRHPDEVDRPHAAHPPLTPGVLSLTSFTSVRSGYSHLPRRKRISVAHMSFQAAAALLKGRSVLDATGQRCRHVKRSFAYPSFLEEDAVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGVPHSASPVSPDGVHIPLKEYSGGRALGPGTQRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHIIITLLVICTYGIAPVGFAQHVTTQLVLKNRGVYESVKYIQQENFWIGPSSIDLIHLGAKFSPCIRKDQQIEQLVRRERDIERTSGCCVQNDRSGCIQTLKKDCSETLATFVKWQNDTGPSDKSDLSQKQPSAVVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQAQSNHTGLLHIDCKIKGRPCCIGTKGSCEITTREYCEFMHGYFHEDATLCSQVHCLDKVCGLLPFLNPEVPDQFYRIWLSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFFNLSAIVLFLFICGLLPWIDNIAHIFGFLSGMLLAFAFLPYITFGTSDKYRKRALILVSLLVFAGLFASLVLWLYIYPINWPWIEYLTCFPFTSRFCEKYELDQVLH

rhbdf2

Inactive rhomboid protein 2

826 amino acids

Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

Belongs to the peptidase S54 family.

93.843 kDa

MASLKKNGSSSRLQDRKPPNLSITIPPVEGERDPKLMQPLTKPVFQKSVSLQEPRGHVAEGGTADVRPGFKRQTSLSQSIKRGTAQWFGVSNDWEGKRQQWQRKSLHHCSLRYGKLKPQYQRDIELPSQETPSFQATESPATHRLPKIVDPLARGRPFRHPDEVDRPRTPHVGLPPQTPGMLSLASFTSVRSGYSRFPRRKRESVAHMSFRAAAALIKGRPILDTPHSRKAGQKRSFIYPSFMDEDTVDAAETLDSSFFSKVDMHDETFSMPDDVFDSPPMSASYFRAPLPIPELMPGAAIEAAKEPVKSVQVYTPDHRRGKRIASQVKHFAFDRKKRLYGLGVVGSWLNRTYRRSISSTVQSQLEHFNSHRPYFAYWITFVHILITILAIATYGIAPIGFAQHTTSELVLRNKGVYESVKYIQQENFWIGPSSIALIHLGAKFSPCIRYDEQIKNLIEKQHGLERESGCCIQNDKSGCVQTHRKDCSETLATFIKWPEHDAPVLDEVTGMKRTSGAVCHQDPRTCEEPASIQPHVWADDITKWPICTYQAMNNHTGIRHMDCEIKGRPCCIGTKGSCEITTREYCTFMHGYFHEEATLCSQVHCLDEVCGLLPFLNPEYPDQFYRLWLSLFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPWKAFLKLLGIVLFLFLFGLLPWIDNIAHIFGFLSGLLLSFSFLPYITFGTADKFRKRAMIIISLLVFVGLFASLVIWLYVYPINWAWIEYLTCLPFTNKFCEKYDIDQVLH