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RAMP3

Gene
RAMP3
Protein
Receptor activity-modifying protein 3
Organism
Sus scrofa
Length
151 amino acids
Function
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL (By similarity).
Similarity
Belongs to the RAMP family.
Mass
17.368 kDa
Sequence
MEATAPRRRHLLPLLLLLLLLCGECPPVSGCNEKRMLAMLPRCGKTFAEMMKKVEVWKWCNLSEFIVYYESFTNCTEVETNVVGCYWPNPLAQSFITGVHRRHFHNCSVDRQQWQDPPDEILIPLIVVPILLTLAMTGLVVWRSKRAAQVV

Gene
RAMP3
Protein
Receptor activity-modifying protein 3
Organism
Homo sapiens
Length
148 amino acids
Function
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
Similarity
Belongs to the RAMP family.
Mass
16.518 kDa
Sequence
METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL

Gene
Ramp3
Protein
Receptor activity-modifying protein 3
Organism
Mus musculus
Length
147 amino acids
Function
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
Similarity
Belongs to the RAMP family.
Mass
16.779 kDa
Sequence
MKTPAQRLHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFADMMQKVAVWKWCNLSEFIVYYESFTNCTEMETNIMGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVVLTVAMAGLVVWRSKHTDRLL

Gene
Ramp3
Protein
Receptor activity-modifying protein 3
Organism
Rattus norvegicus
Length
147 amino acids
Function
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
Similarity
Belongs to the RAMP family.
Mass
16.781 kDa
Sequence
MATPAQRLHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFAEMMQKVDVWKWCNLSEFIVYYESFTNCTEMETNIVGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVLLTVAMAGLVVWRSKRTDRLL

Gene
RAMP3
Protein
Receptor activity-modifying protein 3
Organism
Cavia porcellus
Length
146 amino acids
Function
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL (By similarity).
Similarity
Belongs to the RAMP family.
Mass
16.869 kDa
Sequence
MGTRSRRPQLLWLLLLCGTCARVCGCNETRMLERLPRCGKTFAERMREVAVWKWCDLSQFIVFYESFTNCTEEETVVVGCYWPNPLAQGFITGVHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPILLTVAMTGLVVWRSKRTDQLP