About Products Protein Database Contact

RAB8B

Gene
RAB8B
Protein
Ras-related protein Rab-8B
Organism
Bos taurus
Length
207 amino acids
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.656 kDa
Sequence
MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLEASAKSSMNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITENRSKKTSFFRCLLL

Gene
RAB8B
Protein
Ras-related protein Rab-8B
Organism
Homo sapiens
Length
207 amino acids
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.584 kDa
Sequence
MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCSLL

Gene
Rab8b
Protein
Ras-related protein Rab-8B
Organism
Mus musculus
Length
207 amino acids
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.603 kDa
Sequence
MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITESRSKKTSFFRCSLL

Gene
RAB8B
Protein
Ras-related protein Rab-8B
Organism
Pongo abelii
Length
207 amino acids
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.64 kDa
Sequence
MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCLLL

Gene
Rab8b
Protein
Ras-related protein Rab-8B
Organism
Rattus norvegicus
Length
207 amino acids
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.603 kDa
Sequence
MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITESRSKKTSFFRCSLL

Gene
rab8B
Protein
Ras-related protein Rab-8B
Organism
Dictyostelium discoideum
Length
203 amino acids
Function
Protein transport. Probably involved in vesicular traffic (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
22.642 kDa
Sequence
MTSPATNKPAAYDFLVKLLLIGDSGVGKSCLLLRFSDGSFTPSFIATIGIDFKIRTIELEGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDEKSFGSIRNWIRNIEQHASDSVNKMLIGNKCDMTEKKVVDSSRGKSLADEYGIKFLETSAKNSVNVEEAFIGLAKDIKKRMIDTPNDPDHTICITPNNKKNTCC