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RAB25

Gene
RAB25
Protein
Dehydrin Rab25
Organism
Oryza sativa subsp. japonica
Length
228 amino acids
Similarity
Belongs to the plant dehydrin family.
Mass
23.236 kDa
Sequence
MAEHATGVYGHPYPRVDQYGNPVPPVDQYGNPVPDEPAPRDTAAGYVAPPDPAVSTGDYGLAGAEAPHPHESAVMSGAAAAAVAPGGEAYTRDGGGVVPPAGEKTFAYEGTVSAAGVTGASGQLQPTTREEGHTTLGETLRRSGKSSSSSSSSSEDDGQGGRRKKKSIKEKIKEKLPGSHKQEEQKQAGHTAPAAGTGTGTGTHAAGKHEKKGIVEKIKEKLPGHGHH

Gene
RAB25
Protein
Ras-related protein Rab-25
Organism
Canis lupus familiaris
Length
213 amino acids
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.62 kDa
Sequence
MGNRTEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAIKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLHQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFTKVSKQRQNSTRTNAIALGSAQAGQEPGAGQKRACCISL

Gene
RAB25
Protein
Ras-related protein Rab-25
Organism
Homo sapiens
Length
213 amino acids
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.496 kDa
Sequence
MGNGTEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNSIRTNAITLGSAQAGQEPGPGEKRACCISL

Gene
Rab25
Protein
Ras-related protein Rab-25
Organism
Mus musculus
Length
213 amino acids
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (PubMed:22696678). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.473 kDa
Sequence
MGNRTDEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSKQKQNSTRTSAITLGNAQAGQDPGPGEKRACCISL

Gene
RAB25
Protein
Ras-related protein Rab-25
Organism
Oryctolagus cuniculus
Length
213 amino acids
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway (PubMed:9880326). Together with MYO5B regulates transcytosis (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.428 kDa
Sequence
MGNGKEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVLLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQIQNSPRSNAIALGSAQAGQEPGPGQKRACCINL

Gene
RAB25
Protein
Ras-related protein Rab-25
Organism
Bos taurus
Length
213 amino acids
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.537 kDa
Sequence
MGNRAEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAIKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQSREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNNARTNAVTLGSGPAGQELGPGEKRACCISL