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RAB21

Gene
RAB21
Protein
Ras-related protein Rab-21
Organism
Geodia cydonium
Length
229 amino acids
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
25.345 kDa
Sequence
MASPSDASRRRQATVKAKVVLLGEGAVGKTSLVLRYSENKFNDKHEQTLQASFVEKRLNIGGKRIQLAIWDTAGQERYHALGPIYYRDSQGAIIVYDITDEDSFHKARNWIKELKRMLGDKVTLCIVGNKIDLDRQRTVSEKDALEYAESVGAKHYYTSAKQSKGVAELFLDLAKRILEANPPSSSTPPESQRGAPSSHPPSQPRQRSTLIVTDDSEQPSPKQGGGCCS

Gene
RAB21
Protein
Ras-related protein Rab-21
Organism
Homo sapiens
Length
225 amino acids
Function
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (PubMed:18804435). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PubMed:25648148).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
24.348 kDa
Sequence
MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG

Gene
RAB21
Protein
Ras-related protein Rab-21
Organism
Canis lupus familiaris
Length
223 amino acids
Function
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity). Involved in neurite growth (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
24.161 kDa
Sequence
MAAAGGGGGGAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGAARRGVQIIDDEPQAQSSGGGCCSSG

Gene
Rab21
Protein
Ras-related protein Rab-21
Organism
Rattus norvegicus
Length
223 amino acids
Function
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity). Involved in neurite growth (PubMed:19745841). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
24.163 kDa
Sequence
MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSGSGGCCSSG

Gene
RAB21
Protein
Ras-related protein Rab-21
Organism
Bos taurus
Length
222 amino acids
Function
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
24.146 kDa
Sequence
MAAAGGGGAAAGRTYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKVDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGAARRGVQIIDDEPQAQSVGGGCCSSG

Gene
Rab21
Protein
Ras-related protein Rab-21
Organism
Mus musculus
Length
222 amino acids
Function
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (PubMed:16754960). As a result, may regulate cell adhesion and migration (PubMed:16754960). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (PubMed:18804435). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
24.106 kDa
Sequence
MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSSGGCCSSG

Gene
rab21
Protein
Ras-related protein Rab-21
Organism
Dictyostelium discoideum
Length
212 amino acids
Function
Involved in the regulation of phagocytosis.
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.49 kDa
Sequence
MTDTEKSFKVVLLGEGCVGKTSIVFRYIDNIFNDKHLMTQHAGFFQKHINIGGKRICLTIWDTAGQERFHALGPIYYRGSQGALVVYDITDNDSFIKAKNWIKELKTMLGNDISLCIIGNKCDLEKTRVIPLADAEAYAKSVGAIHYSTSAKLNKGIEELFLDLTRRMILNSSGVVIHSNTNTTGQTTNRSERIPIVPDSDSGNKQPGCCSN

Gene
RAB21
Protein
Water stress-inducible protein Rab21
Organism
Oryza sativa subsp. indica
Length
172 amino acids
Similarity
Belongs to the plant dehydrin family.
Mass
17.326 kDa
Sequence
MEHQGQHGHVTSRVDEYGNPVGTGAGHGQMGTAGMGTHGTTGGMGTHGTTGGMGTHGTTGTGGGQFQPMREEHKTGGVLQRSGSSSSSSSEDDGMGGRRKKGIKEKIKEKLPGGNKGEQQHAMGGTGGAYGQQGHGTGMTTGTTGAHGTTTTDTGEKKGIMDKIKEKLPGQH

Gene
RAB21
Protein
Water stress-inducible protein Rab21
Organism
Oryza sativa subsp. japonica
Length
172 amino acids
Similarity
Belongs to the plant dehydrin family.
Mass
17.326 kDa
Sequence
MEHQGQHGHVTSRVDEYGNPVGTGAGHGQMGTAGMGTHGTTGGMGTHGTTGGMGTHGTTGTGGGQFQPMREEHKTGGVLQRSGSSSSSSSEDDGMGGRRKKGIKEKIKEKLPGGNKGEQQHAMGGTGGAYGQQGHGTGMTTGTTGAHGTTTTDTGEKKGIMDKIKEKLPGQH