Protein
L-proline cis-4-hydroxylase
Organism
Rhizobium meliloti (strain 1021)
Function
Dioxygenase that catalyzes the 2-oxoglutarate-dependent selective hydroxylation of free L-proline to cis-4-hydroxy-L-proline (cis-4-Hyp).
Similarity
Belongs to the L-proline cis-4-/cis-3-hydroxylase family.
Sequence
MSTHFLGKVKFDEARLAEDLSTLEVAEFSSAYSDFACGKWEACVLRNRTGMQEEDIVVSHNAPALATPLSKSLPYLNELVETHFDCSAVRYTRIVRVSENACIIPHSDYLELDETFTRLHLVLDTNSGCANTEEDKIFHMGLGEIWFLDAMLPHSAACFSKTPRLHLMIDFEATAFPESFLRNVEQPVTTRDMVDPRKELTDEVIEGILGFSIIISEANYREIVSILAKLHFFYKADCRSMYDWLKEICKRRGDPALIEKTASLERFFLGHRERGEVMTY