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Pwwp3a

Gene
PWWP3A
Protein
PWWP domain-containing DNA repair factor 3A
Organism
Homo sapiens
Length
710 amino acids
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Similarity
Belongs to the PWWP3A family.
Mass
78.636 kDa
Sequence
MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR

Gene
Pwwp3a
Protein
PWWP domain-containing DNA repair factor 3A
Organism
Rattus norvegicus
Length
698 amino acids
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity).
Similarity
Belongs to the PWWP3A family.
Mass
77.974 kDa
Sequence
MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECSPKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTTKKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGVEGCDPVESSGNIRPLLDSERSKGRLTKRPRLDGGRNPLPRHLGTRTVGAVPSRRSCSGEVTTLRRAGDSDRPEEADPMSSEESTGFKSVHSLLEEEEEEEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCRDMDGEMPARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKEIFDNELLEERNRRRR

Gene
Pwwp3a
Protein
PWWP domain-containing DNA repair factor 3A
Organism
Mus musculus
Length
682 amino acids
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity).
Similarity
Belongs to the PWWP3A family.
Mass
76.069 kDa
Sequence
MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSALEDHLRCQVGPKTGLSESGAGDKSQDDSGLQLDHGQESTTKKRQRNLGEKPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSSGNIRPLSASERSRGCPTKRPRLDGGQNPPTRQLGTRTVGAAPCPRSCSGEVTMLCSAGAGDKPEEDPVSSEESTGFKSTHSLLEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVPERGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR

Gene
PWWP3A
Protein
PWWP domain-containing DNA repair factor 3A
Organism
Bos taurus
Length
641 amino acids
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity).
Similarity
Belongs to the PWWP3A family.
Mass
71.109 kDa
Sequence
MTDAKYVLCRWKKRLWPAKVLAGTEKSAKNKRKKGYFLNVQILSLDKKIKVKSAEAKVLRKVHIEDIASSLASQDGTPAAPLEELTYRRSLRVALDVLNERQGSSSREGTTPRPPRVKPMEPASWPPKPSLSPSFLEDTAGSPGPTRRERMSQRLSGLPAGEEDLEYGVDHKEGLKRSGGLDAPAMCSASGGAQDREASRKQQADWMTPLGKQGRNPAQGPHSGQRVAPSSEGAGQEDGETGAGPAALCSPPGGRDLSPLDGCPAEHLGLDSGQRPRAHMSPHSPAQLGPAEEAADTRPLEEARPLSEEFMEPSAVNSLLEEDEDDEEPPRILLYHEPRSFEVGMLVWHKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPRGRGISVLLRRLKHFDCKEKQALLDEAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISSPVRKSIQQDVQGTRFPQLSGGDPEEPVAGSPQGRRPAYRKVLPDRSRAARDRANQKLVEYIVKARGAESHLRAILRNRKPSRWLKTFLSSGQYMTCVETYLEDEEQLDLVVKYLQGVYKQAGCQLLARGHGDGIRFILDVLLPEAIICAISAVDAVDYKTAEEKYIRGPALSSREKEIFDNQLLEERNRRC