Organism
African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)
Function
Phosphorylates thymidine. ASFV replicates in the cytoplasm of infected cells and contains genes encoding a number of enzymes needed for DNA synthesis, including thymidine kinase. Important for growth in swine macrophages in vitro and is a virus virulence factor in swine (By similarity).
Similarity
Belongs to the thymidine kinase family.
Sequence
MNIIRKLKPGTISLVLGPMFAGKTTFLIHCIYMLERLEKKVVFIKSTKNTRDKTIKTHSGIQLRPKQCKIIESTQLSDVGSLTDIHAVVIDEAHFFDDLIKCRTWADEEKIIILAGLNASFEQKMFPSIVRIFPYCSWVKYIGRTCMKCNRHNACFNVRKNADKTLILAGGSELYVTCCNNCLKKYIY