Pcdh15

Gene

PCDH15

Protein

Protocadherin-15

Organism

Homo sapiens

Length

1955 amino acids

Function

Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.

Mass

216.069 kDa

Sequence

MFRQFYLWTCLASGIILGSLFEICLGQYDDDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAFSLEDYTKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQAALPAAKPAVPAPAPVAAPPPPPPPPPGAHLYEELGDSSILFLLYHFQQSRGNNSVSEDRKHQQVVMPFSSNTIEAHKSAHVDGSLKSNKLKSARKFTFLSDEDDLSAHNPLYKENISQVSTNSDISQRTDFVDPFSPKIQAKSKSLRGPREKIQRLWSQSVSLPRRLMRKVPNRPEIIDLQQWQGTRQKAENENTGICTNKRGSSNPLLTTEEANLTEKEEIRQGETLMIEGTEQLKSLSSDSSFCFPRPHFSFSTLPTVSRTVELKSEPNVISSPAECSLELSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPSASFLSTECVCITGVKCTTNLMPAEKIKSSMTQLSTTTVCKTDPQREPKGILRHVKNLAELEKSVANMYSQIEKNYLRTNVSELQTMCPSEVTNMEITSEQNKGSLNNIVEGTEKQSHSQSTSL

Gene

Pcdh15

Protein

Protocadherin-15

Organism

Mus musculus

Length

1943 amino acids

Function

Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal function.

Mass

214.738 kDa

Sequence

MFLQFAVWKCLPHGILIASLLVVSWGQYDDDWQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITAFDGVQESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQSAMPAAKPAAPVPAAPAPPPPPPPPPPGAHLYEELGESAMHNLFLLYHFEQSRGNNSVPEDRSSHRDGMAFSSSTTESHEPAHVEGPLKESQPNPARTFSFVPDEDNLSTHNPLYMESIGQRSTNSDLQPRTDFEELLAPRTQVKSQSLRGPREKIQRVWNQSVSFPRRLMWKAPNRPETIDLVEWQITNQRAECESARCHPSQRGSSNVLLATEDAHESEKEGGHRDTLIVQQTEQLKSLSSGSSFSSSWSHFSFSTLPTISRAVELGSEPNVVTSPADCTLELSPPLRPRILNSLSSKRETPTCASDTEPKRNSFEIAPHPPSISAPLPHPPLPRPPIAFTTFPLPLSPPNPPPPQLVTFSLPISTPPTSSLPLPPPLSLPPPPRPPAPRLFPQPPSTSIPSTDSISAPAAKCTASATHARETTSTTQPPASNPQWGAEPHRHPKGILRHVKNLAELEKSVSNMYSHIEKNCPPADPSKLHTFCPAEKTGMKITHDQSQETLVRVVEGIDVQPHSQSTSL

Gene

Pcdh15

Protein

Protocadherin-15

Organism

Gallus gallus

Length

1899 amino acids

Function

Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal function (By similarity).

Mass

209.146 kDa

Sequence

MLQQFCLWKWLAVGIAVATILASSLAQNDEDCKLARTGPPATIVPIDEESRNGTILVDNMLIKGTAAGPDPTIELSLKDNVDYWVILDPISQRLYLNSTGRVLDRDPPMSIQSIVVQVQCVNKKVGTIINHEVRIVVRDRNDNSPQFQQQRYYVAVNELTPVGTTIFTGFSGNNGATDIDDGPNGQIEYVIQYNPNDKTSNRTFDIPLTLSGAVVLRERLNYEEKTRYFVIVQANDRAQNLHERRTSTTTLTVDVLDGDDLGPMFLPCVLVNNTRDCRPLTYQASLPELTDPVHVNPISVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPQYFHMNLTTAELTLLKPINRDLHQKFDLVIKAEQDNGHPLPAFANLHIEVLDENNQKPYFTKSTYEGFILESSPVGTTISDSRNLTSPLQITVLDNDVEETKDPQLHLFLNDYNTFFTVTQSGITRYLTLLQPVDREAQQLYTFSMIASDGVQESTPVTVNIVVIDANDNSPTFSNISYNVKIYTDMGPGEGVIKLTAVDADEGPNGQIVYEILAGDQGDFIINDRTGLIAIAPGVVLSVGRSYALTVKASDSAPPAQRRSSITTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRTGAILLNLQAFDREGDPIRYLIENGDPQQVFNLSQSSGLLALGKPLDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNGPVFDMFLPKNLSVQEEEANAFVGQVRATDPDAGVNGQVHYSLANFKNLFRITSNGSIYTAVKLNREVRDYYELIVEATDGAVDPRRSTLTLAIKVLDIDDNSPVFTNASYSVLVPENLPPGTVFLQIEAKDVDLGSNVTYRIRTQEALEYFALNKYTGELSLLKSLDYESFSDTDATFTFLVEAFDSKGTMPPGLATVTVRVKDMNDYSPVFSKTLYRGMVAPDAVKGTVITTVSAEDQDPPGTPASRVRYKVDVVQFPYSASIFDVEENSGRVVTRVNLNEEPSTVFKLVVIAYDDGDPVKFNTTTVEIAVLQPSVIPRFTQDEYRPPPVSESAPKGTVVTVVMAAALNQTIVYSIVSGNEEDVFAINNRTGVISVKKPLDYERVTSYELRVQADSLQVVRSNLRVPSKSNTAKVFIEVKDENDHAPVFTKKMYIGGVSEDAKMFSSVLKVKADDKDTGNYSAMQYRLIIPPIKDGKEGFVIEAYTGLIKTAMLFKNMRRSYFKFQVIATDDYGKGLSSKADVLVSVVNQLDMQVIVSNVPPTLVEQNKDQLIGILERYVQDQIPGATVVVESIGARRFGDGYSEEDYTKSDLMVYAIDPQTNRAIMRNELFKFLDGKLLDINKEFQPYLGQGGRILEIRTPDVVANVKKQAQAVGYTEGALLALAVIIILCCMPAILIVMVSYRQRQAECAKTARIQMALPAGKPASTAANNLYEELGDSTILFLLYHFQQSRGKKSVLEEGDRQRVISSFASRAIEAHKQSNINGSLNNNLPKSSSNITFLSDENPLTTQNPLYVEGVTQSPAAAGLLRKRSDALDTLSPMQLVLRDASLGGSHRAWTVPAHVTKRHAPGSLSRPVIMDPVQWQQERLKAENEGTENQHSRVDISSPLFQKISGPTLTVKEKARQFEQQALQEMKQVKSPDVKSTRSPTHSICLQERDNTLEQSPKSVFASPCLRSSPLSSPTPCEVVEPEPSAVPSVIITHHDYPEELSPPPTRKPTPPSFRIKKPVCQSFLAPQTKGEVTENIPDPPKTPPPPPPLLPPPPPSPPLLPPHPPTLPLASVPSSSSLPSTQHLSPAKHSKSPAKQPAVPPPAAVPEPPPRRELKGILKNIQNLAAIEKSVANMYSQIDKNHVLPKHISKLKPVATPELPTPEAAAEHNQQNGNLSCVVEELEKRFPSQSTAL

Protein

Protocadherin-15: Pcdh15