Protein
Adenylosuccinate synthetase
Organism
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MVSIVLGSQWGDEGKGKITDMLSQDATLCCRAAGGHNAGHTIVHEDVTYDFHILPSGLVSPKCINLIGAGTVFHVPSFFKELAAIEAKGLKGAAQRIFVSDRAHVCFDLHSVVDGLEEKGLGGRKVGTTGKGIGPCYSDKAARRGVRVGEILDEETFERKLRTLDTSYRTRFGDLAYDVEEEIARFKEYRNLLKPHIVDQLEFLQEHKNSPNTLVEGANALMLDLDHGTYPFVTSSSTGLGGAVQALALNPASIKSVIGVVKAYTTRVGSGPFPSEQLNGDGEKLQQVGREFGVTTGRRRRCGWLDLVLCRYSHAINHYTALNLTKLDILDDFDEIKVGVAYILPDGKRTTGTFPADPNVVDKIQVEYVTLPGWKSNTMGVKRYEDLPPNARAYIEFIEREIGGVPVKWIGTGPARDHMIARD