Protein
Phyllocladan-16-alpha-ol synthase
Organism
Phomopsis amygdali
Function
Involved in the synthesis of labdane-related hydrocarbons by catalyzing the conversion of geranylgeranyl diphosphate (GGDP) to phyllocladan-16-alpha-ol in a two step via type B cyclization into a (+)-copalyl diphosphate ((+)-CDP) intermediate.
Similarity
Belongs to the terpene synthase family.
Sequence
MTIMDIDDHSRLRDLAVSLIRQAAEGYSPKYGYGSMSCAAYDTAWVSLVAKPFNGIKKWLFPQSFKFLLENQENDGSWGRQTSPVDRILNTAAPLLSLQRHAREPLQLHDVCEDGDLDDRIHRATLSLQRQLSDWDIASTAHVGFEIIVPALLNLLAAEGLCFSFKAQDELMKVNAAKLKRFDPEVLLYGKHKTTLLHSLEAFVGIIDFDKVVHHKVGGSFMASPSATAAYLMNASCWDDEAEDYIKNVLVNGSGRGHGAVPSAYPSSNFEYSWLLSTLLHAGFTAKDIECPELCDVAGMLENSFIEGQGTIGFARSISSDADDTAKAAFALNKLGYDVSVNEMVKEFEVKNHFQTYPSERDASLSANCNTLLALLHQKQVGAYQPQILKCVKFLTRCWWNTDGPIRDKWNQSHLYSTMLMVQALTEFQAILDQKGLPYGLNTVEMARVSICLFQGCLRTMLQQCEDGSWSHSREQTAYAVLTLGQARRLSTFKHLQSQIDSAIDQAATFIRLHSVDLAQQSLPEFIWTEKVSYTSPLVTEAYCLAALKVATSLVDNPGIVGESLDLGIPSRQRIDKYIWLFHQTPLFRSLPEWQLRASFIEGHLFLPIVNEHRLDVFPRKNMDPDDDYIRLIPFTWTATNNRNFTFASPAWLYDMIMVSVVDYQADEFMEAVAGLTFSEDLSMLVGLIQEVLTPYKTEPASPVTSLIDMSSVQCPRAKLSNIASGDIEEVRTCLRRFASFFLDHPAVRNAQRDDRATAWREVHNYLVAHVRHTQDNMRLNLQEQRRWYVSRNMPYFHWVRSNDDIACPITFGFVTCLVPYLVANPTVERAVIGNESESIVTSSDVSFDSVESKYYADDVCRHITNVTRIYNDCGSVVRDATEKNLNSVNFPEFAVTASGSEKQALRAMGEYERACCQAAFQRLEEASLQTATTEAERAKRRRRLDVWKVFLDTADPYGQIYVVRDFTARSVHVRETGIASTAKDVPLVSSSVPLVGGGPMLVT