pxr1

Protein pxr1

368 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

41.04 kDa

MGLAAPKNKIKLSHDPNNTRWSGNTDSFGHRMMKSQGWTPGEYLGAKDAAHAEFHTEANASHIRVVIKDNTLGLGAKIGSGVGHGECTGLDVFQNLLGRLNGKEEAEIEKEQKGREDLKRAIYAERKWGSIRFVKGGVLIGDKIQDLIDGEKERLKALEIKEKAAESSSEESDSSSDEEEEKSPEPVAEKKKSSKRKREEQEDEEKTSSKKSKKEKKEKKEKKSKKRQSEDEDEKDKSESKKSKKSKKDRKSKSKSTSEAEDETLDESALKARKKEKKEKKRKEKEAAGADTEEASSTSKSSKKSKKDKHKSPSTSKTSTKESTPIVSESSGRSTPMGIRSIRARHIAQKRMASMDVASLNQIFMIKS

PXR1

Protein PXR1

368 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

40.618 kDa

MGLAGAKNKRKLGNDPNNTKWSRNTDTFGQKILRAQGWQPGEYLGAKDAAHAEWHTEANTTHIRVTLKDDTLGLGAKRNNGDECTGLDAFQHLLGRLNGKSDEALEAEQKVRNDVKLSLYIQKKFGMMRFVKGGWLVGDQVKQTPDEEAEEIPDSTETSEAPEPAAVESKKRKADRRSDKEDDKLGKKEKKSKKRKAGSEGDVGGEGGQKEKDKKSKRRKTESDECEEPAVTPKTAESLDEASGASEAGNTKNEKKDKKRDKKEKKERRDKKEKKEKRRIEKAAAESGAETGDSISEEKKRKKKEATSEPSSAPTPTDSNSSTPTGSGYSTPIPTGSSRYLARSRFIAQKKMAFADSAALNQIFMIKS

pxr1

Protein pxr1

367 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

40.681 kDa

MGLSAPKNKIKLSHDPNNTKWSGNTDSFGHRMMKSQGWTPGEYLGAKDAAHAEFHTAANASHIRVVIKDNNLGLGAKIGSGVGHGECTGLDVFQNLLGRLNGKEEAEIEKEQKGREDLKRAIYAERKWGSIRFVRGGVLVGDKIQDLIDGEKERVKALKKGKTAESSSDDSDSSSDEEEEEKSPEPVTEKKKSSKRKREEQEEEEKTSSKKSKKDKKSKKRKSEDEDDKDKSESKKSKKSKKDRKSKSKSTSESETETLDEAAIKARKKEKKEKKRREKEAATAGADTEETSSTSKSSKKNSKKDKHKSSSASESSTKESTPTVTESSGRSTPMGIRSIRARHIAQKRMASMDVASLNQIFMIKSQT

PXR1

Protein PXR1

358 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

39.481 kDa

MGLAAPKNRSKISNDPQNTTWANNTSRFGHRILTSQGWQPGDSLGASDAAHAAHYTVASQSHIRVLLKDDNLGLGAKRGSERAENFGLAGLESILGRLNGKEAEVKKEEERREEIEKRAFVYRKYGMMNFVSGGFLVGDKIKSRDEVKTETQAKVEVKSEPESDGAKEDDRKKKRKRKDRDEAGVEGEEEPKLKRKKKSMDLRDQAKKDIAAESSKDKKGKKSKKDKKAVTSDPEPTSSGVASPASDPEPLTDKARRKAEKKARKEEKRLKKALKKAAKEAAKPMGDVEDLSSESEDESTPSASRPATGTSTPTVSAAGLTFNPRGMHSVRQKWIRSKKSATMDAQAMREIFMIKTPS

PXR1

Protein PXR1

346 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

39.026 kDa

MGLAAPKNKRKLGNDPNNTRWSRNTENFGHRMLRSQGWEPGQYLGPQDASHAVYHTAASASHIKVALKEDNLGLGAKMNRGDECTGLNAFKEMLARLNGKSEAAIEKDKKAREAHAMNVYVERKFGTMRFVSGGFLVGDVIQEKKEDAEAESTDGTPEPAEATVKKEKKRKAGRDDDDEAQSKEERRRAKKQKKSMKETGSGGDDVTSEEDSAKSKSKKSHKSKKEKKRRKEEPASDEQESEDEESREKRRKKEKKERKERRREKREKKLKKKQQREEDSSSSEANSDDETTGVDTGASTPVASGTSTPVSQVSVRHLARRRFIAQKRMAMKDQQALNQIFMIKSS

PXR1

Protein PXR1

345 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

40.308 kDa

MGLAGTKVKQRFGLDPRNTNWSNNNNQFGHQYLTKMGWTPGKGIGLVPDSITTHLKINIKTDNAGLGAKLQKRNKDANELDECSGVDAFQRILGRLNGKEDAVNKVMDMKRDDMIINGKMGIRFVKGEVLSSTWDKEKKALISYANGKNEDKKDKDEVSLLRKRKVEDEEKREVKKSRKDIKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKSDKKEKKEKKDKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKDKLDKESSNAANVESTKSLVSDSSRESTPTPIASRLSVRSKWIKQKRASVMDAKALNEIFMISN

PXR1

Protein PXR1

335 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

38.534 kDa

MGLAATKTKQRFGLDPRNTTWSNDKSRFGHKYLEKLGWEPGKGLGHASHAMSTHIKVTIKDDTMGLGAKLKKKEKKDEFDSGECAGLDVFQRILGRLNGKEEVIADELEKQRKENIINGKWGIHFVKGEVLSSTWDADTMQLKSYSYDKKEITADDAEDAKVSGKHRDRKSRAKREKSNNAALKEKCRDIDRTRKSKRKEKEQEKEKNREKKHNGKEHKEKEHKEKKDKKDKKEKKEKKEKKEKKEKKHKEKSNKRLRSSDSIDDPEATKPSKKSKTKAADSDNVTRDSMLQPRASAASPPPTISTRLSVRSKWIRQKRAAVMDPKALNEIFMVT

PXR1

Protein PXR1

320 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

36.092 kDa

MGLAGPRKRTKISHDPNNTAWSRSTSGYGHKIMSAQGWTPGSFLGASNAAHADHFTAGSAGHIRVILKDDNLGLGAKLRAEDEPTGLDAFQGLLGRLNGKSDEELEKELKKRHDRQLANFVEKRWKTMQFVSGGLLVHEKIQALADVKSAGGEEVQTPQISHDELKSEKRPKKARKKEKRRARGDDTGLDLAEQSPKRKRKDRKENKEKKKSSDDSSYANQGTPSEDALVDKIQKKRKKRKQKDPEPSNTEVHDDSLPPDTRSVSQEEQESRYSAKNESIRKIREHRPMGRQFTRGRHIQQKKLALMDSKSISEIFMVKC

PXR1

Protein PXR1

317 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

35.479 kDa

MGLAGPKKRTKISHDPNNIAWSRSTTGYGHRIMSAQGWTPGAFLGAPGAAHSSCYTAASASHIRVVLKDDTLGLGARPRNPLAEDEPTGLDAFQDLLGRLNGKSEVELVKEQRRREDIKLLSFVERRWKSMAFVPGGYLVKEDPARTLVVAEQANKDDSSDPKSRQETTQKRPKKEKRKEKSRHREEPIDSRSISSKPERGTINSANQTSDDESTNIVPSESKSRKKEKKKKSKKRKMDEVNEEESVPDGRIGCKGILPNKQSAQQSTGERYISGDSMINAREHRPLGRQVIRSRYIQQKKMALLDAKSLNEIFMTS

PXR1

Protein PXR1

316 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

36.976 kDa

MGLAGTKVKQRFGLDPRNTNWSNDTSRFGHQYLERMGWKPGKGLGLVEHATTSHVKVSIKDDNLGLGSKLAKKQKTDEFDSGECSGLDVFQRILGRLNGKEDQINKEIERKRKDNIINGKWGIQFIKGEVLQSTWDKEAKKLLDKGTTKKRKIDSVDSSEESTTSSDSKQHKKKKIKKDRKEKEEKKTEKENSEIKKKKKEKKEKKEKKEKKDKNEKKEKKDKNEKKEKKDKNEEKEKKEKKEKKEKKDKKDKKDKKDKKEKKEVKEVTRDSMLMPKEQLNQQIATRLSVRSKWIKQKRASVMDAKALNEIFMVTS

pxr1

Protein pxr1

307 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

34.033 kDa

MGLAAPRKKTKISHDPNNTSWSRSTDGFGHRILKAQGWTPGGFLGARNATHSDLFTTASASHIRVVLKDDTLGLGARPKRNLLDGPTGLDAFKGLLGRLNGKSDTQLEAEQQKRDDAKLARYAATKWQTVRFISGGLLVQEKDNATASPASQDLRVDFPRETSSHESENGMFKMEPMDSDSQEGGCATAKEEEGKKKEKKKKNKKGKELDMSSRKSREKKQEKRQKKRKISDCDGLDAETANRTSTNVLVAVANDKGTCLLASNGPATSRERQPMGRRIFRSRHIEQKKRALMDDKSLNEVFIILSH

pxr1

Protein pxr1

306 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

33.896 kDa

MGLAAPRKRTKISHDPNNTNWSRSTSGYGHKIMSSQGWTPGSFLGARNAAHADMFTAASASHIRVVVKDDTLGLGARSKRDPLDEPTGLDAFKGLLGRLNGKSDADLEAEQKKHEDAKIARYAATKWHTVTFISGGLLAQEKLVSLSAQKESPGAQHGSHQNRGGLDMQKSEEDANTSIKDNTLKALREEQVSSVPIAEDTSRSKSKRHRKDEQGKKDKKERKTKKRKHMDEPSPIDSDIPERAILETDLQATVTDSRDTTPPVAKVLSKERRPMGRHLLRGRHIAQKKKALMDDRSLNEIFMVKS

pxr1

Protein pxr1

304 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

34.011 kDa

MGLAAPRKKTKISHDPNNTSWSRSTDGFGHRILKAQGWTPGDFLGARNATHSDLFTTASASHIRVVLKDDTLGLGARPKRDLLDGPTGLDAFKGLLGRLNGKSDTQLEAEQQKRDDAKLARYAATKWQTVRFISGGLLVQEKDNATASPASQDLRVDFPRETSSNEHENGMFKTEPMDSYSHQEGCATAREEEGKKKKKKNKKGKEMDMSPRKSREKKQEKIQKKRKIGDCDRLDTETADRTSTKVLVAVANDKGTSLLASNGPSTSRERQPMGRRIFRSRHIEQKKRALMDDKSLNEIFMIKT

pxr1

Protein pxr1

298 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

32.943 kDa

MGLAAPRKRTKISHDPNNTNWARSTSGFGHKILSSQGWTPGSFLGARDAAHADMFTAASAGHIRVVVKDDTLGLGARAGRDPNEPTGLDAFKGLLGRLNGKSDAELAADQRKADDIKLARYAAFKWQAVRFVSGGLLAQEKLERLPERESVQQSRAAVETSDSNRNSENDASKVSKKKKKKTSSDSSSDEQSSRSEKRREKKEKKDKKEKKEKKDKKDKKRKRAEEDNDASQKSASETPAPEKESTGLESDSTSVSVVKASRERRPLGRQIVRGRHIAQKKRALMDDKSLNEIFMVKA

PXR1

Protein PXR1

292 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

33.199 kDa

MGLAGVSKKIKYGKDPRNLGWSNNTERFGHKHMSKLGWKDGEGLGHEDRKAQSITQNIKIVLKDDNVGLGAGLAKADKDEAFGLMDFQKLLGKLNGRAQEIEAEVERQQKDVLRGKFGMVFVSGGLLQGTIEEFNKKRGSEAVEESDSDSEESESESDDDKKSRKSSKKEKKDKKSKKRKADDDSDEEEKKSKKSKKDKKEKKEKKEKKEKKEKKEKKEKKEKKDKKEKKDKKEKKDKKSESPTPHDGMEKPSASSTSALRGRMAGRAKFIRSKRMAVMDEKSLNEIFMVKN

pxr1

Protein pxr1

291 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

32.778 kDa

MGLAAPRKRTKISHDPNNTTWSRSTDGFGHRILKAQGWTPGSFLGPRNAAHSDLFTTASASHIRVVLKDDNLGLGARPKRGLLDEPTGLDAFKGLLGRLNGKSETQLVVEQQKRDDIKLARYAAAKWQAVRFVSGGLLVQESNETLVPPTSQNGQADSEVKNVPQGREEGLADDETTNSDSEDRHSVEKRKKKETNSRGSREKERKREKRQMRRDKKRKTSESTESEAEMQEKTRVQGPSEDVKPTEPKAPTLSRERRPMGRQMFRGRYIAQKKRALMDDKSLNEIFMIST

PXR1

Protein PXR1

288 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

32.893 kDa

MGLAAVKTRQKFGLDPRNTAWSNDQSRFGHKHLMRFGWQPGQGLGTQPVQSMKTHIKVSIKDDNLGLGAKLKKNKGDKIDEFDNGECAGLDVFQRILGRLNGKETEVNKELEIQRKDKILNGKWGVHFVKGDTLASTWDPKTKKLLSYSQMEKDSSSDEESDDDEDEKKKHKIEKKEAKKSKKRKRDSESDSESKKKKKSKKDKKEKKSKKDKKNKKEKESKKDKKSKHKKDKKQEIRTASIESSTSATSIPESVSTRLSVRSKWIKQKRAAVMDSKALNEIFMVTGN

PXR1

Protein PXR1

287 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

33.196 kDa

MGLAGTKTKQRFGLDPRNTAWSNDTSRFGHLQLEKFGWKPGMGLGMSPTSSHKTHIKVSIKDDNLGLGAKIKRTERKDEFDNGECAGLDVFQRILGRLNGKQEEISKELDIQRKQKIIDGKWGIHFVRGDVLASTWDPETKKLKSYSNDKKRSRDDDDEKLSSKNKSKKQKKDKKDKKDKKDKKDKKDKKDKKDKTEKKEKKEKKEKKEKKEKKDKKDKKDKKDKIDKKDKKDKKSLKNNIEVSTTASNIPSTVSTRLSVRSRWIKQKRAATMDSKALNEIFMVTNT

PXR1

Protein PXR1

286 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

32.788 kDa

MGLAGTKVKQRFGLDPRNTSWSNDKSRFGHRYLESMGWAPGKGLGLVEHATTTHVKVSVKDDTVGLGAKLAKRSGTDDLETDSSGLDDFQRILGRLNGRGREVDEALEQKRKDNIINGKWGMHFIKGEVLCSTWDRKSKSHMLKTALEDESEVNFKSSKKRRQSGSEPSRDSTSHAKRMRGDESKKSTRDQSKQERKEKKIKTEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKERDYGNRASPVEPRKHDQISNVGRLSARAKYIKQKRASVMDAKALNEIFMISK

pxr1

Protein pxr1

285 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

31.334 kDa

MGLAAPRKKIKISHDPNNTNWSRSTSGFGHKILSSQGWTPGSFLGARNAAHAEMFTAASASHIKVVLKDDTLGLGARPKRDPLNEPTGLDAFKGLLGRLNGKSDADLQVEQQKRDNVKLARYAATKWQAVTFISGGLLAQEKTTPIVTEEPQGIHKDKQEDKLSATVPGPDSDGVEGSDNIGGQSDQSIKKKKSKSKNHREKKDRKRKHTEEPESTDSGNTNKRSTEKKSKATRDDEESSSTTSKGLSRERRPMGRHVFRGRHIAQKKAALMDEKSLNEIFMVKS

pxr1

Protein pxr1

284 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

31.878 kDa

MGLAGVKKKQQIGVDPRNSKWAKDTNRLGFKLLSSYGWVNGNGLGEKQHGRIHNIKVSLKDDTLGIGAKATNDLEWSGLGEFNAIFGRLNGDESAYGVYAEKAKVQQLTYERQSANEKGLKSLELSRRFVLGGTFTSEFSEWMQKAEEDEDRVCEDASSSDEAKREKRKKHSSKKKSKKKTSTGSALDPKKLEKITKKKKKEHKKKDKESSSKKRKSGSSDKEEKKKKKIKLKDKPESTSSVEKVKEGNRPASIHFHTRRKFLAQKRAAVSDPVALREILGIKG

PXR1

Protein PXR1

276 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

31.392 kDa

MGLAGTKIKQRFGNDPRNTNWSNDTSRFGHQYLAKMGWQQGSGLGLVSHALTTHVKVSIKDDNLGLGAKLHKRKANGDGGLEEEGTAGLDAFQRILGRLNGKENVVNKVLDNVRDDDIINGKWGMRFVKGETLSSTWDKESKKLISYKNIEDDGKKSRKRKADESETKEDKKTLKKHKKEKKDKKEKKEKKKKKEKKDKKDKKDKKNKKDKKDKKDKKDKKDKIRTGSDETLVSKESSATPPPIATRLSARSKWIKQKRASVMDSKALNEIFMITN

PXR1

Protein PXR1

271 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.

Belongs to the PINX1 family.

30.853 kDa

MGLAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSIKDDNLGLGAKLKKKEKQDEFDSGECTGLDVFQRLLGRLNGNEQTISDELDKQRTDNIINGKWGIHFVKGEVLASTWDAENKQLISYSMGKKRPVEGSSDSEVSDRKKTKKVKKEKKVKKVKKEKKEKKEKKDKKEKKVKKEKKEKKEKKLKDKHSKDTNEITRDQMLKPRDSAAVVPDAVSTRLSVRAKWIRQKRAAVMDAKALNEIFMVTD

PXR1

Protein PXR1

271 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites through its action in U18 and U24 snoRNA 3'-end final trimming. Negative regulator of telomerase throughX competition for binding to EST2 with TLC1 (By similarity).

Belongs to the PINX1 family.

31.388 kDa

MGLAATRTKQRFGLDPRNTAWSNDTSRFGHQFLEKFGWKPGMGLGLYPMNSNTSHIKVSIKDDNVGLGAKLKRKDKKDEFDNGECAGLDVFQRILGRLNGKESKISEELDTQRKQKIIDGKWGIHFVKGEVLASTWDPKTHKLRNYSNAKKRKREGDDSEDEDDDDKEDKDSDKKKHKKHKKHKKDKKKDKKDKKEHKKHKKEEKRLKKEKRAEKTKETKKTSKLKSSESASNIPDAVNTRLSVRSKWIKQKRAALMDSKALNEIFMITND

PXR1

Protein PXR1

271 amino acids

Involved in rRNA-processing at A0, A1 and A2 sites through its action in U18 and U24 snoRNA 3'-end final trimming. Negative regulator of telomerase through competition for binding to EST2 with TLC1.

Belongs to the PINX1 family.

31.312 kDa

MGLAATRTKQRFGLDPRNTAWSNDTSRFGHQFLEKFGWKPGMGLGLSPMNSNTSHIKVSIKDDNVGLGAKLKRKDKKDEFDNGECAGLDVFQRILGRLNGKESKISEELDTQRKQKIIDGKWGIHFVKGEVLASTWDPKTHKLRNYSNAKKRKREGDDSEDEDDDDKEDKDSDKKKHKKHKKHKKDKKKDKKDKKEHKKHKKEEKRLKKEKRAEKTKETKKTSKLKSSESASNIPDAVNTRLSVRSKWIKQKRAALMDSKALNEIFMITND