PWP2

Gene

PWP2

Protein

Periodic tryptophan protein 2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

923 amino acids

Function

Required for bud-site selection and cell separation. Also involved in nucleolar processing of pre-18S ribosomal RNA.

Similarity

Belongs to the WD repeat PWP2 family.

Mass

103.983 kDa

Sequence

MKSDFKFSNLLGTVYRQGNITFSDDGKQLLSPVGNRVSVFDLINNKSFTFEYEHRKNIAAIDLNKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEKCSAVKFSPDGRLFALASGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEFTKRPSDDDDNESEDDDKQEEVDISKYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAVSTLKGQISIFNIEDAKQVGNIDCRKDIISGRFNQDRFTAKNSERSKFFTTIHYSFDGMAIVAGGNNNSICLYDVPNEVLLKRFIVSRNMALNGTLEFLNSKKMTEAGSLDLIDDAGENSDLEDRIDNSLPGSQRGGDLSTRKMRPEVRVTSVQFSPTANAFAAASTEGLLIYSTNDTILFDPFDLDVDVTPHSTVEALREKQFLNALVMAFRLNEEYLINKVYEAIPIKEIPLVASNIPAIYLPRILKFIGDFAIESQHIEFNLIWIKALLSASGGYINEHKYLFSTAMRSIQRFIVRVAKEVVNTTTDNKYTYRFLVSTDGSMEDGAADDDEVLLKDDADEDNEENEENDVVMESDDEEGWIGFNGKDNKLPLSNENDSSDEEENEKELP

Protein

Periodic tryptophan protein 2: PWP2

Gene

pwp2

Protein

Periodic tryptophan protein 2 homolog

Organism

Dictyostelium discoideum

Length

922 amino acids

Similarity

Belongs to the WD repeat PWP2 family.

Mass

104.694 kDa

Sequence

MKFGYKFSNLLGTVYNKGNILFTPDGNTVISPVGNRLTVFDLVNHTSITLPIQSKYNIRRLALSPNGQILITSDESGHTLIINLTRQVVLGEYKFFKTPKSILFSPNGAIIAIAVLEKVFLFKTPIIQKQPNPLIRLSVFTHKSAVISMCWSADSLKLMIGCKNGTLLIRQGKSERVSYFQVKGSGIINCFFGNEESTIAYAVTPTGLASWDYKTNEEMEQEKLERVENGETAYLREEEMDEEKLKVITENQRLYKGRWIFKGFKKFENYGVKCKVKTVCFHLKSKLLLVGFSTGQFILYEMPGFNQLYKLNISSHGISTSAINNTGEWLAFGCSELGQLLVWEWRSETYILKQQGHSYNMNTVAYSPDGQTIATGGEDGKVKIWNTTSGYCYITFTEHEGPVTAVKYSPVSSQNVVFSAGVDGTIRAFDLVRYRNFRTFVSPNKTQFSCLAVDPSGEIIAAGSLDSFEIYVWSVRTGRLTDILSGHQSPVCELAFDPINPFLASASWDKSCKIWNIFEDREIRESIQHTSDVLTCAYSQDGKKFIVSCLDGTIQIYETSTWGQIGLIDGKNDIMGGRGYKDEILAKNNSAGRAFTKIAFTPNGECIIAGGNSKYICIYHIDQQVLIKKYSTSSNLSLDGITLDINWKRVGEFGHLDAMEKDFDSDDDLYQQNKEYLTGSSKGDLSKRTTKKKQKTTSISVSPTGRAWAVSTTEGLLIYSLDDFLFFDPTDLSIDINPDSILSELNLKNYLKSLIMSIKLNEKPIIEKVFESIPFNEIQLVCQEFPIYYLKNFIQFLSGYFEKNHHLEFQMKWVKLISIYHGKYIKTNSLSMITSLRNLQKTITQTYNDISKVCDDNIFSMEYFKTVLLKELKSQEETNKISKKSQKYKKYLESKKNKEQEEDQFSDDEETVYQNNKKNKNK

Protein

Periodic tryptophan protein 2 homolog: pwp2

Gene

PWP2

Protein

Periodic tryptophan protein 2 homolog

Organism

Homo sapiens

Length

919 amino acids

Similarity

Belongs to the WD repeat PWP2 family.

Mass

102.452 kDa

Sequence

MKFAYRFSNLLGTVYRRGNLNFTCDGNSVISPVGNRVTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPPAGWKADLLQREEEEEEEEDQEGDRETTIRGKATPAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGQEDGVAIPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATTTEGLLIYSLDTRVLFDPFELDTSVTPGRVREALRQQDFTRAILMALRLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLLMLHGQKLKSRAGTLLPVIQFLQKSIQRHLDDLSKLCSWNHYNMQYALAVSKQRGTKRSLDPLGSEEEAEASEDDSLHLLGGGGRDSEEEMLA

Protein

Periodic tryptophan protein 2 homolog: PWP2

Gene

Pwp2

Protein

Periodic tryptophan protein 2 homolog

Organism

Mus musculus

Length

919 amino acids

Similarity

Belongs to the WD repeat PWP2 family.

Mass

102.91 kDa

Sequence

MKFAYRFSNLLGTVYRCGNLNFTHDGNSVISPVGNRVTVFDLKNNRSNTLPLATKYNIKCVGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCIDWTDDSKCFVVGSKDMSTWVFGAERWDNLIYYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCDTPPEGLRLKAPRGWKADILQREKEEEEEDEEEGDRETTIRGKTTPAEQERVGKVKYSRLAKYFLNKEGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWRTKETLTLTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDLKTGRKELDKITAKHSAKGKAFTTLCYSADGQSILAGGMSKFVCLYHVREQILVKRFELSCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGEENGVAVPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATSTEGLLIFSLDAQMLFDPFELDTSVTPGRIREALRQREFTRAILMAFRLNEKKLAQEALEAVPQNEIEVVSTSLPELYVVKVLEFLAASFEESRHLEFYLIWTQKLLMSHGQRLKSRAGQLLPVVQFLQKGLQRHLDDVSKLCDWNRFNIQYVLAVSKQRGMKRTLEPVDTEEDSDASDEDSLHLLRAAGEEEEEEMLI

Protein

Periodic tryptophan protein 2 homolog: Pwp2

Gene

PWP2

Protein

Periodic tryptophan protein 2 homolog

Organism

Pongo abelii

Length

918 amino acids

Similarity

Belongs to the WD repeat PWP2 family.

Mass

102.286 kDa

Sequence

MKFAYRFSNLLGTVYRRGNLNFTCDGNSVISPVGNRVTVFDLKNNKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPPAGWKADLLQREQEEEEEEGDRETTIRGKATPAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSILASASWDKTERLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHHLKTGRKELDKITAKHAAKGKAFTTLCYSADGQSILAGGMSKFVCIYHVREQILMKRFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGQEDGVAIPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATTTEGLLIFSLDTRVLFDPFELDTSITPGRVREALRQQDFTRAILMALRLNESKLVQEALEAVPSGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHRLLMLHGQKLKSRAGTLLPVIQFLQKSIQRHLDDLSKLCSWNRYNMQYALAVSKQRGTKRSLDPLGSEEEAEASEDDSLHLLGGGGRDSEEGMLAES

Protein

Periodic tryptophan protein 2 homolog: PWP2

Gene

PWP2

Protein

Periodic tryptophan protein 2

Organism

Arabidopsis thaliana

Length

900 amino acids

Function

Involved in nucleolar processing of pre-18S ribosomal RNA. Plays a role early in ribosome biogenesis, especially in the maturation of 5.8S rRNA (PubMed:23382868). Required for guard cell functions (PubMed:23185391).

Similarity

Belongs to the WD repeat PWP2 family.

Mass

100.471 kDa

Sequence

MEFRFENLLGAPYRGGNAVITKNTQLISPVGNRVSVTDLSKNHSVTLPLETSTNICRLASSPDGTFLLAVDEQNRCLFINLPRRVVLHRITFKDKVGALKFSPNGKFIAVGIGKLVEIWRSPGFRRAVLPFERVRTFANSDDKVVSLEWSLDSDYLLVGSRDLAARLFCVRKLKGVLNKPFLFLGHRDSVVGCFFGVDKMTNKVNRAFTIARDGYIFSWGYTEKDVKMDESEDGHSEPPSPVTPDRADEVMVENGGGVGTELKKRKEYDGKGLESDEEGDDDDEEYMHRGKWVLLRKDGCNQASAKVTACDYHQGLDMVVVGFSNGVFGLYQMPDFICIHLLSISRQKLTTAVFNERGNWLTFGCAKLGQLLVWDWRTETYILKQQGHYFDVNCVTYSPDSQLLATGADDNKVKVWNVMSGTCFITFTEHTNAVTALHFMADNHSLLSASLDGTVRAWDFKRYKNYKTYTTPTPRQFVSLTADPSGDVVCAGTLDSFEIFVWSKKTGQIKDILSGHEAPVHGLMFSPLTQLLASSSWDYTVRLWDVFASKGTVETFRHNHDVLTVAFRPDGKQLASSTLDGQINFWDTIEGVLMYTIEGRRDIAGGRVMTDRRSAANSSSGKCFTTLCYSADGGYILAAGTSRYICMYDIADQVLLRRFQISHNLSLDGVLDFLHSKKMTEAGPIDLIDDDNSDEEGGIDKQSRGNLGYDLPGSRPNRGRPIIRTKSLSIAPTGRSFAAATTEGVLIFSIDDTFIFDPTDLDIDVTPEAVEAAIEEDEVSRALALSMRLNEDSLIKKCIFAVAPADIKAVAISVRQKYLERLMEALVDLLENCPHLEFILHWCQEICKAHGSSIQRNYRTLLPALRSLQKAITRAHQDLADMCSSNEYTLRYLCSVPNNH

Protein

Periodic tryptophan protein 2: PWP2