PTEN1

Gene

PTEN1

Protein

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1

Organism

Arabidopsis thaliana

Length

412 amino acids

Function

Protein tyrosine phosphatase that exhibits also lipid phosphatase activity. Can use phosphatidylinositol substrates such as PtdIns(3,4,5)P(3) as substrate. Pollen-specific phosphatase required for pollen development.

Similarity

Belongs to the PTEN phosphatase protein family.

Mass

47.355 kDa

Sequence

MGLKLSRGPVKEKSPLEFTRVHILTYFTTNSYLRNLVSKKRRRLIIGGYDLDMSYISDKLLAMSFPAERMRAVYRNPLWQVKSVLDMRHPDHYKVYNLCIEESYDPDNFYGRVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPKNIAVVHCMAGKGRTGLMVSAYLVYGGMSAEEALEMYASRRTTNNNGVSIPSQRRYVKYWSDLLSFSKKGPPEVKLPQEHSRELLRIRLYDTANVDSVFFVVSELQEVPNEMYRPSVELARGCCRQFKKGYCRSSSPRYYISHVNCDSEEDEEVTDGEEPHLVVQMDTESSIIDEKTCLDFYFDKPVRVSGDIRITFYQKMIGSRLFYTCFNTAFITNGLLQFSIGELDKVGGNGRSISGPDFSLELLFGPACSKFGKFLSRDDLSLS

Protein

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1: PTEN1