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PSPTO_3506

Gene
PSPTO_3506
Protein
Probable S-methyl-5'-thioinosine phosphorylase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
246 amino acids
Function
Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
Similarity
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Mass
26.388 kDa
Sequence
MTVYAIIGGTGLTQLEGLNIRQSLPMNTPYGAPSGEIQIGDYAGREVMFLARHGHPHRLPPHQVNYRANIWALKQAGAEAILAVNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHTFFADDLEEVTHIDFSYPYSEALRVRLVAALAAEGCAFSDRGVYACTQGPRLETVAEIIRLERDGCDIVGMTGMPEAALARELELEYACLALVVNPAAGKSTAVITMAEIEQALRDGMGKVKATLARVLSAS