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PSMD3

Gene
PSMD3
Protein
26S proteasome non-ATPase regulatory subunit 3
Organism
Bos taurus
Length
534 amino acids
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Similarity
Belongs to the proteasome subunit S3 family.
Mass
60.957 kDa
Sequence
MKQEGSARRRGADKAKPPPGGGEQEPPPPPAPQDVEMKEEAAAGGGSTGETAGKTAAAAAEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDTDGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP

Gene
PSMD3
Protein
26S proteasome non-ATPase regulatory subunit 3
Organism
Homo sapiens
Length
534 amino acids
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Similarity
Belongs to the proteasome subunit S3 family.
Mass
60.978 kDa
Sequence
MKQEGSARRRGADKAKPPPGGGEQEPPPPPAPQDVEMKEEAATGGGSTGEADGKTAAAAAEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVQGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASTPLLPEVEAYLQLLVVIFMMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP

Gene
Psmd3
Protein
26S proteasome non-ATPase regulatory subunit 3
Organism
Mus musculus
Length
530 amino acids
Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Similarity
Belongs to the proteasome subunit S3 family.
Mass
60.718 kDa
Sequence
MKQEGSARRRGADKAKPPPGGEQEPPPPAPQDVEMKEEAAAGSGSTGEGDGKAAATEHSQRELDTVTLEDIKEHVRQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP

Gene
psmD3
Protein
26S proteasome non-ATPase regulatory subunit 3
Organism
Dictyostelium discoideum
Length
504 amino acids
Function
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Similarity
Belongs to the proteasome subunit S3 family.
Mass
57.439 kDa
Sequence
MADIEMSEASKTPVVAEEVVDPVQKANEASLLTFADLKKNIGLIDKGVDTKEMRFIISVLRQTQSIRKKLNYKVLNQIVNFAFSHQNHATKKNFLLSFLKSDGSSMDIDSTTQAEKETTPSSSSSHLNIEVESYIHLLVLIYLIDQKKYEDATKCSSALMETVQSNTRITLYPLSSKIFFYYSLSYEMTNNLHEVRSTLLSALRTATLRHNDEGQATIINLLLRNYLEYNLFEQADKLLANTQFPESASSNQFARYFYYQGRIRAIQLEYAESFKFLTQAIRKAPQNTAGGFRRTVYKLLSIVQLLMGEIPERNTFSQKQLKIALKPYFHLTEAVRVGDLGSFNQALEQNSDIFKSDQTFTLVQRLRSNVIKAGLKKLNTAYSRISFNDICTKLKFDGTTQDIMFIIAKTIKDGVIDATINYEGGYLQSRENIDAYSTQEPLHAFSNRIDICLKIHNDSLKAMRFHPDLNKAETEKIAEVAKTIKEEMERQAEESSDNEGDSDF