Protein
Peroxiredoxin-like 2C
Function
May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
Similarity
Belongs to the peroxiredoxin-like PRXL2 family. PRXL2C subfamily.
Sequence
MAAPSEAPVTRQVSGHAAPAPVPSGPASWQPLAAAVAELPVLDASGRPVLFGELFRERRAIVVFVRHFLCYICKEYVEDLAKIPKSFLQEANVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEIASSGQSPHVKSNILSGSIRSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFIHHDRNRLDHKPINSVLQLVGVQHVDFTSRPSVIHV