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PRP5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
1211 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
133.782 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRSRRDDDRYEKSRRDDLRSYRRSRSPERRYRDRDRDSYRRRDRSVDRRDDHRDEDSYRSSRRDRSRDRRRSRDRGDDRDHRRKSRERDYRSRRDDSRDRARRRTDDSADLKHKSRRDDSRTRNLDSKPREASKPSTPAPTAPTEDEKRAERLAKLEAWKQKQAAERERKQREAAAAGGARSILEEIDRKSGLSPAVGSPQSPATPTTDATPTPYSGKFDPKAIVRNAAPAPSTPAVLGNDVAVPQSAKASASSSSMNNHVQANKHPAANSTTSCKLYIPTIRFLQIANVTCTATSTVKRNVGGFGLGAKQVADAEKSSAVKTLGFGEEESKRKKLERLPTPPLEDAKDDMGAVDAAVEDEDDVDMQDGGTEEENAAAARAAAERREERLQSEALRAQSKEAALQSNGDVEMNDVPHQAESEKMEVDAAEEEVDPLDAFMSELAETAPPKKTTGARFTKAKDQQPEAMFGDEHDVDLTAVGEGDADDFLAIANKAKKKKDIPTVDHEKMEYEPFRKKFYTEPSNLAEMTDEEAASLRLELDGIKVRGVDVPKPVMKWSQCGLGVQTLDVIQKLGYENPTSIQSQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIRDQRPLENMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIVVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANIRPDRQTVLFSATFPRNMEALARKSLTKPIEIVVGGKSVVAPEITQIVEVRNEDTKFVRLLEILGNLYSDDANEDARALIFVDRQEAADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALRQSGQKVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERRTYKTGEEGEDEEDKEDKAEKADERFSKIVSSVQSAAAAATTPLPGVPKGIDLDGKITVHRTEKDPAGASKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEPGPGENPKLYILVEGETELAVTNAMRELMRLLKEGTLAAADSDARAPVGGRYNVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
1207 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
133.942 kDa
Sequence
MARPRDSRSPSPAGSTHSSRRFRNDDRRDRDRRNDGRDHRRRTRSRSPDPRNRDRDRDRDRDRARDRDNYRRRDRSLDRRDDNHYRGGRRDNRERDRRRSRDRFDDRIRSPMTDRRRNRSRENDRDVRRRDDSRSRISGRREGTTDSPARSNRDDGRNQKTPLDDSGNGGASQVRHTLLDFECIADGLQAQTPKAEGGQADVDKKAERLAKLEAWKKKKESASQKQKEVNPSQTRNLLAEMDKKASGASSKTVSPSVSAIASPAATPTVESPAASYSGKFDPKAIAKKSAASRAHDASKPALGSLEGQPEKISVPVKQATTASALPANRTKASGFGFVKTNAETEKLTAKRKLDLDEEDTTKRKLTKLPALPIEADDTPYADQDDDESDGDNFAENEEEAAAAARAAHERRLQAENQMDTAEEETKPTDVETNGDVAMNNNASQPEPATQMEVDEEDDVDPLDAFMADLKQTDVRQPTKTSTTQKIQEPEAYFSDDEYDFNKKDEGDASALLAITAKRKKKDIPTIDYSKIEIEPIRKNFWHEPAELSLLTEAEVADLRLELDGIKVNGKDVPKPVQKWAQCGLTRQTLDVVDNLGYEKPTPIQMQALPALMSGRDVIGVAKTGSGKTVAFLLPMFRHIKDQPPLKDTDGPIGLIMTPTRELAVQIHKDCKPFLKMMGLRAVCAYGGAPIREQIAELKRGAEIIVCTPGRMIDLLAANQGRVTNLKRVTYVVLDEADRMFDMGFEPQVMKIFANMRPDRQTILFSATMPRIIDSLTKKVLKNPIEVTVGGRSVVAKEIEQIVEVRDEPSKFHRVLELLGELYDRDEDARTLIFVERQEKADDLLKELMMKGYPCMSIHGGKDQIDRDSTISDFKKGVVPILIATSVAARGLDVKQLKLVINYDAPNHLEDYVHRAGRTGRAGNTGVAVTFVTPEQENCAPGIAKALEQSGQPIPDRLNEMRKAHREKVKSGKAKDTSGFGGKGLDRLDQEREAARLRERKVHKAEGEEEEVTEDKKEDEDEKAEKALDAIRAAASGVLARESAKADDADAKSMPPVKTSGVVKDKAKDPLDKVSSAVSAINSRLGKAGQLRAGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGNFYPAGKEVPAGAEPKLYILIEGDTEVVVSSALTELTRLLREGTIAAVDADSRAPASGRYTIT
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Coccidioides immitis (strain RS)
Length
1197 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
133.147 kDa
Sequence
MARETRSPSPVGSTHSSSKRSRRNDDYLDRSRRDDGRGHRRSRSPPRRHRDRDWDRHRDRDRDRDRDRVRDRERGRDRERDRDTYRKSDRSVDRRDYRDDVRDDTSYRPSRRDRSRPRYHSRDREDGREYRHRSRDRRRRDDSADSKSIAKRNESRDRVSSKDFTGKSREVSKPSTPAPPIAQTDEEKKAERLAKLEAWKQKQAAEKERKQKELAAAGGARSILAEIDKRSTLRQAGVSQETPAPQESESASAKKFDPKTITKNAAAQPERLSLLGNDVAVPNTTTSSEVAGRNGADSTRIAPLKPRGNVSGFGFGAKSAAELEKASHKRALDFGDEESSRKKLMKLPDPSLEDNDTPNGTVNGAEEEEDDDGDIDMQDGGTEEENAAAARAAAEKREERLQNQTVALESQPEQQPETLETDQNGSAEPMDVEDEEEIDPLDAFMSGLKDSVTVDASKYRKNVSKPKQEPEAIFGDEDDVDLKAMDFEADDFLAITSKTRKKKDLPTVNHETIDYEPFRKSFYTEPVDLAELNDEEVAALRLELDGIKVRGVDVPKPVQKWSQCGLGVQTLDVIRKLGYEQPTSIQSQAIPAIMSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLENMEGPVGLIMTPTRELATQIHKECKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIIVCTPGRMIDLLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIISNIRPSRQTVLFSATFPRNMEALARKTLTKPVEIIVGGRSVVAQEITQIVEVRPENTKFVRLLELLGNLYSDDNNEDARALIFVDRQEAADGLLRDLMRKGYPCMSIHGGKDQVDRDSTIDDFKAGIFPVLIATSVAARGLDVKQLKLVINYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALKQSGQSVPEAVQKMVDSFLEKVKSGKEKASASGFGGKGLERLDQERDAARNRERKTYKTGEEGEEDEEKEKKEKDKGEELFAKAASAVQSSSAPTPSATPGVPKGIDLDGKITVHKTERATPSTTGTNPLDKVGSAVADIHARLNKAGVMRSGVPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSYYPPGKEPGPNENPKLYILVEGDTELVVTNAMRELMRLLKEGTIAAADSEARAPASGRYNVL
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
1193 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
131.584 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRSRRDDDRYEKSRRDDGRSYRRSRSPERRYRDRDRDSYRRRDRSIDRRDDHRDEDSYRPSRRDRSRDRRRSRDRGDDRDHRRKSRERDYRSRRDDSRDRARRRTDDSADLKHKSRRDDSRTRNLDSKSRETSKPSTPAPAAPTEDEKRAERLAKLEAWKQKQAAERERKQREAAAAGGARSILEEIDRKSGLSPAVGSPQSPAATPTTDATPAPYAGKFDPKAIVRNAVPAPSTPAVLGNDVAVPQSAKASASLSSMNNHVQANKPPAAISTASSTLTVKRNVGGFGLGARQVADAEKSSAVKTLGFGEEESKRKKLERLPTPPLEDAKDDTGAVDAAVEDEDDVDMQDGGTEEENAAAARAAAERREERLQSEALRAQSKEAAPQPNGDVEMDDVSHQAESEKMEVDAAEEEVDPLDAFMSELAETAPPKKTTGARFAKAKEQQPEAMFGDEHDVDLTAVGEGDADDFLAIANKAKKKKDIPAVDHEKMEYEPFRKKFYTEPSNLAEMTDEEAASLRLELDGIKVRGVDVPKPVMKWSQCGLGVQTLDVIHRLGYENPTSIQSQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIRDQRPLENMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIVVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANIRPDRQTVLFSATFPRNMEALARKSLTKPIEIVVGGKSVVAPEITQIVEVRNEDTKFVRLLEILGNLYSDDANEDARALIFVDRQEAADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPILIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALRQSGQKVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERRTYKTGEEGEDEEDKEDKAEKADERFSKVVSSVQSAAAAATTPLPGVPKGIDLDGKITVHRTEKDPAGASKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEPGPGENPKLYILVEGETELAVTNAMRELMRLLKEGTLAAADSDARAPVGGRYNVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
1192 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
131.673 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRSRRDDDRYEKSRREDGRGHRRSRSPERRYRDRDRDRESYRRRDRSLDRRDDYRNDGGYRSNRRDRSRDRRRSRDRGDDRDHRRRSRDRDYRSRRDDSRDKARRRTDDSADLKHKSRRDDSRTRDLDSKSRDTSKPSTPAPAAQTEDEKRAERLAKLEAWKQKQAAEKERKQREAAAAGGARSILEEIDRKSGLSPAVGSPKSPVTPTTDATPAPYAGKFDPKAIKRNAAPTPSAPLVLGNDVAVPQIAKASATFSSMNNHAQANKPAAALSTAPSTLKSKRNVGGFGLGAKQVADAEKPSAVKTLGFGEEESTRKKLERLPTPPLEDGKDETVAADMGAEDEDDDMQDGETEEENAAAARAAAERREERLQNEALRAQSSEKVPQTNGDVEMNDAPIQAEAENMEVDVEEEDVDPLDAFMSELAESAPPKKTFGTKFSKAKEQQPEAMFGDENDVDLTAVGEGDADDFLAIANKAKKKKDIPTVNHEKVEYEPFRKKFYTEPSNLAQMTDEEAASLRLELDGIKVRGVDVPKPVQKWSQCGLGVQALDVIERLGYESPTSIQSQAIPAIMSGRDVIGVAKTGSGKTVAFLIPMFRHIKDQRPLDNMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIADLKRGAEIVVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANIRPDRQTVLFSATFPRNMEALARKALTKPIEIIVGGRSVVAPEITQIVEVRNEDTKFVRLLEILGNLYSDDANEDARSLIFVERQEAADALLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALKQSGQQVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARNRERRTYKTGEEGEDEEEKEDKAEKADERFNKALSSVQSAAAAAPTLPGVPKGIDLDGKITVHRTEKDPAGTSKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAYHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPPGKVPGPNENAKLYILVEGETELAVTNAMRELMRLLKEGTIAAADSDARAPVGGRYNVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
1186 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
131.044 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRSRRDDDRYERSRRDDGRSYRRSRSPEKRYRDRERDRDSYRRRDRSLDRRADYRDEDTYRPSRRDRSRDRRRSRDRDDDRDYRRRSRDRDFRSRRDDSRDRARRRTDDSADLKHKSRRDDSRERARDSVPRSREASKPSTPAANTGPTDDEKRAERLAKLEAWKQKQAAEKERKQREAAAAGGTRSILDEIDRKSGLSPAVGSPQSSATPIDAAPASYTGKFDPKAIAKNAAPAPAVKSVLGDDIAVPPSAKTSATFPSTKTEVQANKPSATSSKASSLKVKGNVGSFGLGTKQAADTEKASATKTLGFGEEESTRRKLERLPTPPLDDAKDSNKEEDVTAEDEDDDVDMQDGDTEEENAAAARAAAERREERLQNEARDSQSNGDVQMSDASNQKAPDKMEVDAQEEEEVDPLDAFMSELAESAPPKKTAGAKFAKAKPQQPEALFGDENDMDMTAVGDGDADDFLAIANKAKKKKDIPTVDHKKVEYEPFRKKFYTEPSDLAAMSEEEAASLRLELDGIKVRGVEVPRPVSKWSQCGLGVQTLDVIDRLGYSAPTSIQAQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIKDQRPLENMEGPVGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIADLKRGAEIIVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKILANVRPDKQTVLFSATFPRNMEALARKTLNKPVEIVVGGRSVVAPEITQIVEVRSEDKKFIRLLELLGNLYSTDENEDARALIFVERQEGADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEDQERYSVDIAKALKQSGQSVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERKTYKTGDEGEEEEEKEEKNEKAEEQFNKVLSSVQSAAAPSLPGVPKGIDLDGKITVHKTEKDANGSKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYATGKEPGPGENPKLYILVEGETELSVTNAMRELMRLLKEGTIAAADSDARAPVGGRYNVL
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
1184 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
127.644 kDa
Sequence
MHGHRASASAIHPDYPVTHRESTWRRATLIVQGSTATVDDTLRPAVPARGLQAAEIAREIATEIATAVAEVVTTVTVLEIDVTTAETTAAMTVETTAETAAAHVHHPVARGHRTAEMIVTAETTAGTTAGTTVAMIGTGVEVPRHVGQARDVLQPHRPRTSAATREERVNPEKQKEDKLAERAAKLLEWKKRKEAERLAQEKAGTPGSGASPAGSVPSTPAVAATPPPREAKPTVAKSKVPKPATEKVKQKQPEKSSFKLDESAAARPLIAKPAGKPVAIAAASKYHHIDYKCSNQLTQTDGAAAAATTKANGNIGSFGLKTKSTAEEDISSKALLDDEIDTGKRKLQALPVFATHDEPETTAGVEDDAAMSDIGTDDDETNAQLQAKLQSRRAELSHDQAADKDTNMEEVPTADNTGDQMDVDDNAGAEEDDVDPLDAFMADLSVPQQPSRAAPQGETMFNDDLEPEQTAVEGEDLLALRAAKKKKKEVPTINHEKVEYEPFRKDFYTEPAEITQMSAEDVADLRHELDGIKVKPDDVPRPVTKWAQMGLLQQTMDVFTRVGYARPTAIQAQAIPIAESGRDLIGVAKTGSGKTLAFGIPMIRHVLDQRPLKPADGPIGLILAPTRELSLQIVNELKPFLNASGITIKCAYGGQPISDQIAMIKRGGIHILCATAGRLIDLLQSNSGRVLSFRRITYVVLDEADRMFDMGFEPQVMKILASIRPDRQTILFSATFPKTMAALARKALDKPAEVIIGGRSKVAPEITQHITIVPPSYEKKIAKLLHHLGQTFSDDENAQVLIFTERQETAEDLLSKLFKAKYFAVNTIHGAKDQTDRNEAINEFKQGLLNILIATSVAARGLDVPGLALVYNFDCPTHLEDYVHRCGRTGRAGNKGLAVTLIENPGQERFAVHIVKALKESGAEVPDDLQAMANAFHEKVKSGTEKYYNVGFKGKGLDELDASRALDKKREKRALKLGDDDASDDEPDLPKLKKPEASGPGVAKSTNGDAAAEPVQDEPAWKKLLLGKIVVNKTERAETGKPTTAKERAMAAARKIDGNLSRKGTVHAGQPIDNKGPDAGLYHSTLEINDFPQKARWAVTNRTNVAKILDATGVSITTKGNFYGPGKEPGETDLPKLYILVEGDTEGVVTQAMLELTRLLTDATVAAEEAASTRGPTGRYSVMS
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Length
1181 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
130.643 kDa
Sequence
MARHGDTRSPSPVGSTHSSSRRSRRDDDRYERTKRDDGRSYRRSRSPERRYRERDRESYRRRERSIARRDDYRDEDSYRPIRRDRSRDRRRSRDRGDDRDYRRRSRERDFRCRRDDSRDRARRRADDSTDLKHKSRRDSSRDRPKDSASRSRETSKPATPAPTAVPTDEEKRAERLAKLEAWKQKQAAERERKQREAAAAGGARSLLDEIDRKSGLSPAVGSPQSPATPSTTADATPAPYAGKFDPKAIAKSAAPAQAASNVLGDDVAVPTAVKASATSTTTKVQANKPSTASKASAPLKAKGVVGRFGLGTKQAADMEKSSATKTLGFGEEESTRRKLERLPTPPLDDANDTNKPEDNAEDDDDVDMHEGDTEEQTAAAARAAAERREERLQNEASKTNGDTTMNDAPHSQEGEKMEVDAKEEEEIDPLDAFMSELVETAPPKKTTGAKFSKAKEQQPEAIFGDENDPDITAVGEGDADDFLAIANKAKKKKDIPKVDHAKMEYEPFRKKFYTEPSDLAQMSEGELASLRLELDGIKVRGVDVPKPVQKWSQCGLGVQTLDVIDRLGYENPTSIQSQAIPAIMSGRDVIGVAKTGSGKTVAFLIPMFRHIKDQRPLENMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIVVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANVRPDRQTVLFSATFPRNMEALARKTLNKPVEIVVGGKSVVAPEITQIVEVRNEDKKFVRLLELLGNLYSSDENEDARALIFVERQEAADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEDQERFSVDIAKALKQSGQKVPEPVQQMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERRTYKTGEEGEEEEEKEEKNEQAEERFNKVLSSVQSASAPSLPGVPKGIDLDGKITVHRTEKDANGAKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPTGKEPGPGENPKLYILVEGETELAVTNAMRELMRLLKEGTLAAADSDARAPVGGRYNVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Length
1180 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
130.133 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRNRRDDDRYERSRRDDGRSYRRSRSPERRYRERERDRDRDAFRRRDRSLDRRDEDSYRPGRRERSRDRRRSRERDDYRRRSRDRDYRSRREDSRDRARRRTDDSADLKYKSRRDDSRDRAKDAPRSRETSKPSTPAATAAPTEDEKRAERLAKLEAWKQKQAAEKERKQREAAAAGGARSILEEIDRKSGLSPAVSSPQSPATPGVDATPGTYTGKFDPKAIAKSASSTPAPPAVLGNDVAVPPSVKPVTTIPSQVKPKSTTSASATLKAKGNVGGFGLGTKQAADTEKSTATKTLGFGEEESTRRKLERLPTPPLEDAKDVNGTADGAADEDEDDVDMQDGGTEEEAAAAARAAAERREERLQSEAIKAQSNGAESNDTVMGDAPSQEAADNMEVDAQEEEEIDPLDAFMSELAESAPPKKKVGAKFSRTKEQQPEALFGDEHDIDMTAVGDGDADDFLAIANKAKKKKDIPAVDHKKVEYETFRKKFYTEPSDLAQMSDEEAASLRLELDGIKVRGVDVPKPVQKWSQCGLGVQTLDVIDKLGYEKTTSIQAQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIKDQRPLDNMEGPVGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIADLKRGAEIIVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANIRPDRQTVLFSATFPRNMEALARKTLTKPIEIVVGGKSVVAPEITQIVEVRNDDQKFVRLLELLGNLYSSDENEDARALIFVDRQEAADALLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEDQERYSVDIAKALKQSGQKVPEPVQKLVDAFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERRTYKTGEEGEDEEEKEEKNEQAEERFNKAISSVQSTAAPSLPGVPKGIDLDGKITVHKTEKDPNSTSKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPTGKVPGPGENPKLYILVEGETELAVTNAMRELMRLLKEGTIAAADSDARAPVGGRYNVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
1173 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
129.992 kDa
Sequence
MARHGDTRSPSPVGSTYSSSRRSRRDDDRYERKRDDGRSYRRSRSPERRYRERDRDRDSYRRRDHSVDRRDSHRDEDNYRRRDRSRDRRRSRDRDHDRDYRRRSRSRDRDYRSRRDDSRDRVRRRTDDSADLKRKSRRDDSRDRTRGAEPKSREASTPAIPTRTGPTDDEKRAERLAKLEAWKQKQAAEKERKQKEAEASGGPRNILEEIDRKSGLSPAVSSPQSPATQGVDAAPAAYAGKFDPKAIAKNAAQTPAAPSVLGNDVAVPSSAKTSNAQTARVQASKASGNAPSPAVLKAKGNVGSFGLGTKQVADNEKSIATKTLGFGEEESTRRKLERLPTPPLDDADASKTAETNADDDDDVDMQDGETEEDAAAAARVAAERREERLQNESLTKTTNGNTTAKAEEADKMEVDAQEEELDPLDAFMSELAESAPPKKKAGAKFSKAQEPEAIFGDEHDVSMTAVGEGDAEDFLAIASKAKKKKDIPTVDHNKVEYEPFRRKFYTEPSDLAQMSEEEAANLRLELDGIKVRGLDVPKPVQKWSQCGLGIQTLDVIDKLGFASLTSIQAQAIPAIMSGRDVIGVAKTGSGKTMAFLIPMFRHIKDQRPLENMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIIVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKILSNVRPDRQTVLFSATFPRNMEALARKTLTKPIEIVVGGRSVVAPEITQIVEVCNEEKKFVRLLELLGNLYSTDENEDARSLIFVDRQEAADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEDQERYSVDIAKALKQSGQEVPEAVQKLVDSFLEKVKAGKEKASNSGFGGKGLERLDQERDAARMRERRTYKTGEEGEDEEEKDEKKNEQAEEQFNKVLSAVQSTSAQLPGVPKGIDLDGKITVHKREVDPNAPNNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEPGPGENPKLYILVEGETELSVTNAMRELMRLLKEGTIAAVDSESRAPASGRYSVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
1156 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
126.208 kDa
Sequence
MSGYDNRDDYRHSSSSSHHRSRNSKHDSSSSSYRSHGYAPTRRRSRSPSSYHSSSRSHRDHTTDPYPNGSGHDRRHDRDRNRERDRRDHDSPIEAAPSPDGRRFHVEGAPRQGGRRRWDEGAPTPPTAAAPVHVSDPTRSSLNTQLPSRPIVAPPGMAPGPPPSLPSSTPIVPSTGISISPEEQAKLAKKARLEAWRKEQAAKKALEEARQRARSIASAVAPSSQRTESFSSSSTPQTAPTSINAAGLRTLSLRTDPSRTTAQNRSRTMMDDASESSKRIHLSRLGDLPPLDPSIDTAHIATTSVDAEDDDHQLGVAPPTQGSSAAAMDVDDDDEEEDPLDAFMLTVKSQVAQVNDDDRRKASASGGHERTQAKSKAVVLGRDDSDGEAEDQYEELDELDRVGMATEDLLALAAKKVKKKDLVTVDHSAIDYEPFNKAFYHPPAEIQDMSEELANQIRLEMDAITVRGRDCPKPLTKWSHCGLPASCLDVIKRLGYSAPTPIQSQAMPAIMSGRDIIGVAKTGSGKTMAFLLPMFRHIKDQRPVEPSEGPVGIIMTPTRELAVQIYREMRPFIKALGLRAACVYGGAPISEQIAEMKKTADIVVATPGRLIDLLTANSGRVTNLYRVTYLVLDEADRMFDMGFEPQVMKILNNIRPDRQTVLFSATFPKQMESLARKVLKNKPLEITVGGRSVVAAEIEQIVEVRSEDTKFHRLLEILGELYNREKDARTLIFVDRQEAADDLLKDLIRKGYVTMSLHGGKDQVDRDETISDFKAGNVPIVTATSVAARGLDVKQLKLVINYDVPNHMEDYVHRAGRTGRAGQKGTCITFITPEQDRYARDIIAALKASAAHVPPELEAMAASFKEKLAAGKAKAAGSGFGGKGLDRFELDREKTLKAQKSAYGEADDDAKAAAAGDSSEDKAKTGAPPGASSSEDQLSKIQGMKIEIMQGAAPESVRDNKTLSASQEASAAAAAAAAARSKAEPEQELKEAAQLKAQEAALEAAKAHGADTTKLAAVLENIRRQANARKEAAKNSELDKHKDRKARDPDATDYHAIVPINDFPQRARWRVTNKETMRHLIESTGASITNKGVFYKEGTEPQPGEPPKLQLLIESNTKSMVEDAVREIQRLLVEATQAVLEAEARNPGTTGRYTVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Botryotinia fuckeliana (strain B05.10)
Length
1151 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
127.33 kDa
Sequence
MARHRDSRSPSPTGSHHSSRRNRRDDNGRRDRDRRDDVRGQRRSRSPDRRERDRDMNRRRDRSVGRLNDDYHRSGRRERSRDRRSYADRERSPDRRRRRSRERDYRDRRDDSYDDRARRRREDSTDSWSRSRGDETRGQTPRSDAGAKVNDAPKVSTPAVQTEEQKKAERLAKLEAWKKKMAEDKERKEKELAAGGTRKLLDAIDQKANGSPSLTSPNSPTTPATPATPGDLAPPTNYAGKFDPKAIAKKAVASSSSAHTLGKDLPLKELSKASATLTSTVKGLQADKKPTAFSSTSKVSALPKTRGNLSVFGLGAKVTDNEKTSQKRALDFDEDEGSRKKLEKLPSLPMANTEEDDAALANGVEEQDDDDDADLEAAGTEEEAAAAARAAAEKREERLQEAEAQPHTNGDVQMEDAPQPDSTAMDEDEEIDPLDAFMEEMGDPFSLPKNNATFIKDNIKSQPQEPEPLFGDDDVDLKALDADPDEILAIANKARKKKDIPTINYSALDLPPFRKNFYTEPTELAEMTEAEIADLRLELDGIKVAGKDVPKPVQKWSQCGLDVKSLDVITKLGYERPTSIQMQAIPAIMSGRDVIGVAKTGSGKTIAFLLPMFRHIRDQRPLKGSDGPIGLIMTPTRELATQIHKECKPFLKAMGLRAVCAYGGAIIKDQIADLKRGAEIIVCTPGRMIELLAANSGRVTNLQRVTYVVLDEADRMFDMGFEPQVMKVFNNIRPNRQTILFSATMPRIMDALAKKTLQSPVEIVVGGRSVVAPEITQIVEVREEKEKFHRLLELLGELYNTDEDARTLIFVDRQEKADDLLKDLMRKGYPCMSIHGGKDQVDRDSTIDDFKAGVVPIMIATSVAARGLDVKQLKLVVNFDAPNHLEDYVHRAGRTGRAGNTGTAVTFITEEQEQYSVGIAKALEQSGQEVPDRLNEMRKSYKDKVKSGAKKESSGFRGKGLERFDAEREATKARELVQPAASTAPPKLLGVPKGIDLDGDIKVHRTEPAATTGSKLDKVTSAIDAINARLNKTGQLRSGVPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEVQADPKLYILVEGDTEVVVTNAMRELMRLLKEGTMAAADAEGRAPVGGRYTVT
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
prp5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5
Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
Length
1114 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
122.005 kDa
Sequence
MADAIEIEEMMLEDRDIAVVLEVPTRRRRSRERDYRDRRDDSYDDRARRRREDSTDSWSRSRGDENRGQTPRSDSGAKVHDAPKASAPAAQTEEQKKAERLAKLEAWKKKMAEDKERKEKELAAGGTRKLLDDIDQKANGSSSQPSPNTPTTPSTSAISGDLAPTNYAGKFDPKAIAKKAVASSSSAHALGRDLPLKELSKTSATLTSTVKGLQADKKPTAFNSTSKVSALPKTRGNLSVFGLGAKVTDNEKTYQKRALDFDEDEGSRKKLEKLPTLPMANSKEDDAALANGIEGQDDDDDAELEAAGTEEEAAAAARAAAEKREERLQEAESQPHTNGDVHMEDAPQADSTAMDEDEEIDPLDAFMEEMGDPFSLPKSNTTFVKNNTKSQPQEPEALFGDDDVDLKALDADPDEILAIANKARKKKDIPTINYANLNLPPFRKNFYTEPAELVDMTEAEINDLRLELDGIKVAGKDVPKPVQKWSQCGLDVKSLDVIKKLGYDKPTSIQMQAIPAIMSGRDVIGVAKTGSGKTIAFLLPMFRHIRDQRPLKNSDGPIGLIMTPTRELATQIHKECKPFLKAMGLRAVCAYGGAIIKDQIADLKRGAEIIVCTPGRMIELLAANSGRVTNLQRVTYVVLDEADRMFDMGFEPQVMKVFNNIRPNRQTILFSATMPRIMDALAKKTLQSPVEIVVGGRSVVAPEITQIVEVREEKEKFHRLLELLGELYNADEDARTLIFVDRQEKADDLLKDLMRKGYPCMSIHGGKDQVDRDSTIDDFKAGVVPIMIATSVAARGLDVKQLKLVVNFDAPNHLEDYVHRAGRTGRAGNTGTAVTFITEEQEQYSVGIAKALEQSGQEVPERLNEMRKSYKDKVKSGAKKESSGFGGKGLERFDAEREATKARERKIHKLNGDDDEEEKEEKDDDVLLKAASVVQPASASTAPPKLLGVPKGIDLDGDIKVHRTETAASSSGSKNPLDKVTSAIDAINARLNKTGQLRSGVPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEVQAGGDPKLYILVEGDTEVVVTNAMRELMRLLKEGTMAAADAEGRAPASGRYTVT
Protein
Pre-mRNA-processing ATP-dependent RNA helicase prp5: prp5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
1072 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
119.71 kDa
Sequence
MPRSPYRSSNRSYRSPSPSRYDRSHPSSSSRRQDDRKASRYDDDYSRDRERDRERERDRTRDYRDRDRDYDRRRDKDRYRDDDRDRRRRDDKDDRRREERDRGSDRKRDSERRSPMSTIRVDPIVSLASPVPETEEEKKRKAKERLETWKRQRALKEGKSAAATPEPKSTAPPPVTSGLPPKPTAFSLSRIGLPLKPTNPTPLKRSMAALDDEDTSDRKLQKLDLPDFDPEVQSGDAAQVGSIGADLAVADGDEDDDTVVKKEEEKEEKMDIDKKAEEDEEEDPLDAFMRDNVQQVVEVNKADAKRMGLRVAEDGSDDENQGQVVEKDKLAEAEALLQQAAAKSRKKDLPPPDHSKIDYEPFRKAFYVPPVEVLEMDEEEAELVRLEMDGIKIRGQDAPKPVRNWGAFGLPQGCLDVIKHQGWETPTSIQAQAIPAIMSGRDVIGIAKTGSGKTVAFLLPMLRHVRDQRPVSGSEGPIAVVMSPTRELASQIYKECQPFLKVLNIRASCCVGGSSISEDIAAMKKGAEVVICTPGRMIDLLTANNGRVTNVRRTTYIVMDEADRMFDMGFEPQVMKIINNVRPSAQKVLFSATFPKTMESLARRILVKPLEITVGGRSVVAPEIDQRVEVRDGDTKFTRLLEILGEMGEEHKDEDDFRTLIFVDRQESADDLFRELLQRGYVCASLHGGKEQVDRDEAIKNFKNGDVPIIVATSVAARGLDVKELKLVINYDAPNHMEDYVHRAGRTGRAGNKGTCITFITPEQERFSVDIVRALEASKAFIPDDLKKMSDSFLGKIKSGKARAAGSGYSGKGLERIERRREEKDRAEKTTYGDTSEALSLSSREGAVIPYKAKTNEFKPPETSHKGEADYTFTEIKVDIVNGPAPDRVSSQPVFNPKNAVASLPAQTLAALEKAKKEGRGVDAANLANVVAKLTQSIELTKAEKLGLAAATSAPRLAPGARTKDPDATDWHAIFPINDYPQKARWKATNKEQMTLLQEVSGASITMRGRFYPPGEEPALGGEPKLSLLIESNDEMRVRAAVEEIRRVLVEGSVQALNAVDRAGASGGRYAV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
1072 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
119.71 kDa
Sequence
MPRSPYRSSNRSYRSPSPSRYDRSHPSSSSRRQDDRKASRYDDDYSRDRERDRERERDRTRDYRDRDRDYDRRRDKDRYRDDDRDRRRRDDKDDRRREERDRGSDRKRDSERRSPMSTIRVDPIVSLASPVPETEEEKKRKAKERLETWKRQRALKEGKSAAATPEPKSTAPPPVTSGLPPKPTAFSLSRIGLPLKPTNPTPLKRSMAALDDEDTSDRKLQKLDLPDFDPEVQSGDAAQVGSIGADLAVADGDEDDDTVVKKEEEKEEKMDIDKKAEEDEEEDPLDAFMRDNVQQVVEVNKADAKRMGLRVAEDGSDDENQGQVVEKDKLAEAEALLQQAAAKSRKKDLPPPDHSKIDYEPFRKAFYVPPVEVLEMDEEEAELVRLEMDGIKIRGQDAPKPVRNWGAFGLPQGCLDVIKHQGWETPTSIQAQAIPAIMSGRDVIGIAKTGSGKTVAFLLPMLRHVRDQRPVSGSEGPIAVVMSPTRELASQIYKECQPFLKVLNIRASCCVGGSSISEDIAAMKKGAEVVICTPGRMIDLLTANNGRVTNVRRTTYIVMDEADRMFDMGFEPQVMKIINNVRPSAQKVLFSATFPKTMESLARRILVKPLEITVGGRSVVAPEIDQRVEVRDGDTKFTRLLEILGEMGEEHKDEDDFRTLIFVDRQESADDLFRELLQRGYVCASLHGGKEQVDRDEAIKNFKNGDVPIIVATSVAARGLDVKELKLVINYDAPNHMEDYVHRAGRTGRAGNKGTCITFITPEQERFSVDIVRALEASKAFIPDDLKKMSDSFLGKIKSGKARAAGSGYSGKGLERIERRREEKDRAEKTTYGDTSEALSLSSREGAVIPYKAKTNEFKPPETSHKGEADYTFTEIKVDIVNGPAPDRVSSQPVFNPKNAVASLPAQTLAALEKAKKEGRGVDAANLANVVAKLTQSIELTKAEKLGLAAATSAPRLAPGARTKDPDATDWHAIFPINDYPQKARWKATNKEQMTLLQEVSGASITMRGRFYPPGEEPALGGEPKLSLLIESNDEMRVRAAVEEIRRVLVEGSVQALNAVDRAGASGGRYAV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Length
1064 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
114.993 kDa
Sequence
MTITEAVAVMEEAIETVVGHATEAQTERDRQIAEDNGAEMVTGTTAPAKSTPTQAQTEAEKKAERLRKLQAMKEKHAQKEAKEAAVTAGSTRMLLAEMDQKASGTPGPNSPVAGAMSPAPTSPAPPMPYAGKFDPKAIAKSSKAARPQSPTRLGDVKLAAPAPKPLGLKKEANLKGAGLLPANRAKSSTKRKIDMDDEEVIKRKLVKLPDFVPENADSTPDAEGEGEEEADDLDLLMAQNEEEMAEAHRVLQERRDERIQKEGMAMDVDTETPNGETKDEAENEANVESKDEAVLPAPSMDVDEDVDPLDAFMADLEQTGSAGGIGSVPARQKQKAGKGFEPEAYFSDDDYGYEEDKADPSSILAMASKKKKKDIPTIDYSKIELNQIRKNFWVEPQELSQMTEDDIADLRLELDGIKVSGKNVPKPVQKWSQCGLTRPILDVVEGLGYEKPTSIQMQALPVIMSGRDVIGVAKTGSGKTMAFVLPMLRHIKDQDPVTGDDGAIALIMTPTRELCTQIYSDLLPFAKALKLRAIAAYGGNAIKDQIAELKRGAEIIVATPGRMIDLLAANSGRVTNLKRATYLVLDEADRMFDMGFEPQVMKIFNNVRPDRQTILFSATMPRIIDALTKKVLREPVEIQVGGRSVVAPEITQIVEILDEGKKFVRLLELLGELYADDDDVRALIFVERQEKADDLLREVLRRGYGCMSIHGGKDQEDRNSTISDFKKGVCPIMIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFITEEQENCAPGIAKALEQSGQPVPEQLNEMRKAWKEKVKTGKAKDASGFGGKGLERLDKEREAARVRERKTHKAEGEEDDFKEEETAEDAAKKDKAKSAILAAASAIVSRESAKADASEAKPLPAAAEGAVKGGVTVNAGKGGALDKAASAISEINARLARAGQLRPGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATSTSITTKGNYYPPGKEPPSGSDPKLYILIEGDTELAVGKALSELTRLLREGTIAAADAESRAPASGRYTIA
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
1012 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
108.571 kDa
Sequence
METEQQQRKDSVASAGSTRQLLAQMDVKATGSPSAMTSPGAASPATAQSAEDASPAVPYGGKFDPKAIAKKASARHQSPTVLGALQGRAAEKTAVSIAAPAKGSAASSLPQGKPISGFGFGKASNDDKVPTKRKLNLDDEEISKRKLAKLPDLSLETTDDAPYVNQDDDEDSDGDNFAGTEEEAAAAARAAHERREERILQQSMAMETDEANPAAEGQVNGSEPAVSSANAPEEAQAKPQTDSMDVDTKEDDDEVDPLDAFMADLTEPSFGPASKPVKTLSSAKVLPTPEAYFSDDDEFGASTKEGVDAKAIMAMAAKRKKKEIPTIDYSKLDIVPVRKNFWVEPYELSEMTEAEVAELRLELDGIKVSGKDVPKPVQKWSLCGLTRPILDVIAKLEYDKPTAIQMQALPVIMSGRDVVGVAKTGSGKTMAFLLPMFRHIKDQEPVKDNEGPIGLILTPTRELAVQIFRDCKPFLKTLGLRAVCAYGGPPIKDQIADLKRGAEIVVATTGRMIDLLAANQGRVVSLRRTTYIVLDEADRMFDMGFEPQVMKIFANVRPDRQTVLFSATMPKIMDALVKKVLKNPVEIEVGGKSVVASEITQIVEIRDEKSKFNRLLELLGELYKDDDDVRSLIFVERQEKADELLRELLRKGYGCMSLHGGKDQVDRDSTISDFKSGVCPVMIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFVTEEQENCAIGIAKALEQSGQPVPEKLIEMRKAFREKVKAGKAKDQSGFGGKGLEKLDKEREAARNRERKTHKAEGEEDDAEDDKKTTKNDEKTDKASSAILGAASAIVSRDAAKAEAEAKAAEGGSTPTAAATPAAGGKGGALDKAASAINEINARLARAGQLRPGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGNYYPPGKDPPAGADPKLYILIEGDTELVVGNALSELTRLLKEGTMAAADAESRAPASGRYTIT
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)
Length
994 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
112.203 kDa
Sequence
MTLPSGDSSITNNTNQTLNEDEKRRLRREKLAALRQKKLAEAQNGEGNKRQEGNGNGTGQGTGNVAADLTTKRNEKQKVENSFAKLNSTSIDHSSTETQATSLEEKQRLLLKRQGQRIEDWKKNRSADTASHFPQRAKENLSHTRIAITKKSTFKLPKIKRNNNKRVFGFVNEDKEGGGGKEEEDEEEEFTKKKILKIANDDARDYLNYGEKFRKPVLEEAEDDLDQFIESISKSESFVDNNNGGKQVQEQNVEEEKQQQQQQQLEQEQEQEQEQLEKLPRYLAVNNNNNEDTDEVYRYEEDFDDEFDEDDEDDINKRLSAKLNKLQNTAKELKEIDHTSIEYPKFRKHFYQVPFEMSTMDNRELDMLRLELDNVRARGKNVPPPFLTWGQLLMPESVMSVIQNDLGFAKPSPIQCQAIPIVLSGRDMIGVAKTGSGKTLSYVLPMVRHIQDQLFPKPGEGPIGLVLSPTRELALQIEKEILKFSSTMDLKVCCCYGGSNIENQISELKRGVNVIVATPGRLIDLLAANGGRITTLRRTTFVVLDEADRMFDMGFEPQIQKIFTQIRPDKQTVLFSATFPRKLEQLAKKVLHNPIEIIVGGVSVVASEISQEIILFEDTDQLMNHKIQKLEDILSRFFDLGKNTGKVLVFVEKQTDADKLVSVLLKKAIPCIAIHGGKDQIDRKHAIREFSDDQSGINVLIATSIAARGLDVRNLDLVVNFEPPSHLEDYVHRVGRTGRAGKHGEAITFVDNTQEKEISILVKALKMSSRAVDSKLQEIADKFMKKIESGEEKRSSGFGGKGLEKLQNVRETNMQLQKKMFGNFKKEDGKKSHRDLSEQVDYFGSSSSSSSFPSSSNTTTTTTTTSTASAIEIPTFEIIEGNSPETSGPDKCKFYCRVTINDLPQKVRWGIVQRESLSKIIEASKTSITTRGQFYPPQSKQTPTNDQPKLYLLIEGLTRKAVEEAAVLIRDKMLQGVEAMRLDNHSAPTGRYVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
974 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
107.223 kDa
Sequence
MPRDREYDQWGYSGTRRDGGGRYGYRDRSRDERDRFRDVRDRDRDRDRDRERDRGGYRQDPRDRRYSRSRERERRGSGSRDRSRDRSRDRSRDAHRPPPSGRPHQPSGHDSTKSSNSMSETSSTSQVTGTTPNTTNATPSQAEIDAKKAAKLAKVAEWKRKKELERSKSASASPAPSTAPASPKAGFSMSGLSGLRKATDQGQVKRKMFFGGDSDEEDAGRKPAKLLKKLGEKEGSGKSEGKGRGGSQSEAKNASEKNGAASEPAEVDPLDAYMSSLTLPTTTSVSIADSTPLENLNVWEQVDTLEKSQDPTLDLSALSKRKEIAIVDHSKQVYEDFRRQFYVESSELADMTEAETNELRLSLDGIKIRGKDCPKPISKWTQLGLPGPTMGVLNDLRYDKPTSIQAQAIPAVMSGRDVISVAKTGSGKTLAFLLPMLRHIKHRVGVETHTTTLSGASSHPLGVIITPTRELCVQIYRDLRPFLAALELTAVCAYGGSPIKDQIAALKKGTHIIVCTPGRMIDLLAANQGRVLSLSRVTFLVIDEADRMFDMGFEPQVLKLTQSIRPDRQTVLFSATFPKKMEQLARRVLSKRSSDSLGPIEIIVGARSVVASEITQFVEVFQNEKSKFPRLLEVLGKYFAQGFFDEQSEGRVGTGESAATPIPNPKCLIFVERQESADSLLKELIQSGYPCLSIHGGKEQADRDQAISDFKSGLVSVLIATSVAARGLDVKGLGLVVNWDSPNHMEDYVHRVGRTGRAGQKGTALTFLLSDQERLAAEISRAIKSSGNAPPAPVQLMTERFEFKVRSGTEKRHMYGFSGKGLERLQDERDATREHERRAYEGDEAGEAETESSTPAASTANTDIIPKPVIVVTPPDSKSPTTAYHTTLQINDFPQQARYRASSNTSVSRVIANTGCSITAKGEYYPPGRIPGPKDEPKLFILIEGTSERAVKLAHHELSELLVSGLVKGARYQV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
913 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
102.477 kDa
Sequence
MNSTGSNYSLKHNNTQDNNHNSEESVTNKTGELDKPGVKDGQALSKEEKLKRRQEQLAAWMQKRQQENQEPSGKVTISATDETNIDKEKLIRQQRIEEWKRKRLQKSEGLETDRSKIKTFEVKSSNEPTIKINASMKKTITPANGRSKKRPIFGDEDEDDEKESKPKFKKPTLDLAEIEEKKPEKSIDTEIDELDKYLSLLEEKEQGVENKKIENHDDDGIANGPGVGNVNESDDEEIDEDQKQQDILSSKLNRLQNKQKQLDDVDHNQIQYHPFRKDFYTEPTEISKLPEEEVANLRLKLDGIKVRGVNCTRPIIRWSQLGLPSTIMSIIEGRLNYSSPSSIQAQAIPAIMSGRDIIGVAKTGSGKTLSFVLPLLRHIQDQPPLKKGDGPIGLIMTPTRELALQIHKELNHFTKKLNISSCCCFGGSSIESQIAELKKGAQIIVGTPGRIIDLLAANSGRVTNLQRVTYLVLDEADRMFDMGFEPQVTKVFTRVRPDRQTVLFSATFPRKMELLAKKILDNPMEIVVGGISVVASEITQKVELFENEDDKSLEEAKFSKLLSTLNDYGDKDAECKILIFVEKQIAADELLVKLLTEKYPCLAIHGGKDQIDRKHAIREFSSSNSGVNILIATSIAARGLDVKGLNLVINYEAASHMEDYVHRVGRTGRAGRKGTAITFVSSKQGRAITDLVKAMRLSKVSEDEINPRLIEISTKFLEGVKSGKEKYNFGFSGKGLDNLQEIRESNRDLERKVYGEENDSSTFKANEKKQNKTDIHQSDLDVKLPDFHIIEGRAPETAGPDKCKFHSRITINDLPQKARWITVNRDSLSKVIESTGTSITNKGNYYPPNSKIPKTIKQNGKEVTPPPKLYLLVEGLTEKAVHDAIILLREKMIEGLEVAAKEESMGPTGKYTV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
884 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
100.398 kDa
Sequence
MSIDNQASTALKNSGQEVKNNTNQTSELSKEEKLRKRREQLELWRQKKQQQQQEQEEVQNKAKKTEDSTNNTSTEEVKKSRQQRIEEWKRARLQKQQATKEKTTTITIKKKVHSQTTRPTLKRNLDFGDDEDDRKNSHRPVFKKPSLEYDEISEHQNDKESEDELDVFLASIRESELKSDNTKAEKAIESIPEGDVENEKENDDYGGDGDEEDESDEESRLQDLISTKLTKLQNKGKELQSIDHSQENYQEFRKVFYREAYELSALSDEQVELIRQDLDNIKVKGTDVPRPILKWSHLALPTNLSSVIHDKLKFEKPSAIQSQALPTILSGRDVIGIAKTGSGKTLSYVLPMLRHIQDQQFSKDNQGPIGLILSPTRELALQIEKEILNFTKRNNNLRVCCCYGGSSIENQINELKKGVEIIVGTPGRVIDLLAANSGRVLNLKRCTFVVLDEADRMFDLGFEPQVNKILTQIRPDRQTVLFSATFPRKMETLAKQILTDPVVIIVGGISVVAPEIKQEVVLFETSAEEQDKYKQQRVEKLHDILTNYQIEHPDSKILVFTEKQNDADELVANLLSNKYPAIAIHGGKDQMDRKYAIKEFASMDSGINILIATSIAARGLDVRNLGLVINFDPPNHMEDYVHRVGRTGRAGAKGNAITFVSSSQPKEVFNLVKALKLSHSDIDPKLEEIANKFVTKVKAGKEKISSGFGGKGLDNLQEVRDNKLKLEKQRFGDQQPQRQQEETETKKSNDEPVPDIALPEFNIIEGNTPETSGPDKCKFYCRIVINDLPQKVRWNIVQRESLSKIIDESRTSITTRGQYYPPGSKPLSNDQERNGSLAKLYLLVEGLTLQSVTEAITLIKKKMLESLDILNQRENLQPTGRYVV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
875 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
98.404 kDa
Sequence
MDNTVTNDSDESKLSKEEKLKKRREQLALWRQKKEQDSKNGEKEMNSNATTSSDDKQKLRQQRMEEWKKKRAQETKIDSKESVKESPKQENSILKRLASSIKKQELPFTKKRILFDEEEEDESKRKPKFKKPTLDGHTEDLQHREDDPNGKIDELDDFIASLSKQESSSNDIPSQIIEDEQLEVENEGDSEDEEIDQDKKQQELLSSKFQKLQNEKQLETIDHSTMNYSDFRKNFYQEPSEIQNWTAEQVESIRLELDGIKVAGSNVPRPVLKWSHLGLPASYMNIIEDKLEYKAPTSIQSQALPAIMSGRDIIGVAKTGSGKTLSFVLPMLRHIQDQPDLKDGEGPIGLILSPTRELAVQIHKEITNFTKRLGMTACCCYGGSPIESQIAELKKGAQILVGTPGRIIELLAANSGRITNLRRVTYVVLDEADRMFDLGFEPQVTKISSQIRPESQTVLFSATFPRKIELLAKRLLYNPLEIIVGGISVVASEITQKVELFEKGESSQLEDEKFDRLLNILNVFSIESKHSKVLIFVEKQSAADDLLVKLLGSNHPCLTIHGGKDQIDRKYAIKEFSSKDSGVDILIATSIAARGLDVKGLDLVINYDPPNHMEDYVHRVGRTGRAGMKGTAITFVSSDQERSVTDLVRAMTMSKIPEDEIPSRLIEIRNQFLEKVKAGKFKYSFGFGGKGLEKLQQIRDSTRSLQKKEYGPNDDDDVNFVADKTNGTAKKDGATSLPASEVAVDLPDFQVIEGRAPETSGPDKSKFHSRITINDLPQRARWFVVNRDSLSKIIESTSTSITNKGQYYAPNVKVPQTVTVNGKESPAPPRLYLLVEGLTEQSVREANSLIRDKMIEGLEVASKESNMAPTGKYKV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
Length
872 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
99.451 kDa
Sequence
MSADNVSSIDPEKERISRERREKLAKWRAKKALMDSQNELKKETVPLEVKNSKITNNENDSTSRSKLLERQHKLQEWKRKKREREEEQLIKEQENTKETSSHSKKKNKKQNRGSQKRQITFDDSDDETTGESKDSFDKSEIVVEKSDMSGSKNNNEDDPLEAYMKSLVNGGQPLNHKIGENILDEDGDDNSIEEDDEFSNSESDEESSRYKRISKAKAKKKVKEIKFTIKDLEPFPKSFYSEPDEVKLMTDDEVEEMRLSLGGIKVKGKHCPKLITRWSQLGLPTDIMNLITKELKYDEPTAIQSQAIPAIMSGRDLIGISKTGSGKTISYILPMLRQIKAQRTLSKNETGPLGLILAPTRELALQINEEVEKFTKQDRSIRTICCTGGSEMKKQINDLKRGVEIVVATPGRLIDILTLNSGKLISTKRITFVVMDEADRLFDMGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAARILTDPLTVTINSNNLVNENVNQSFYIEDNENDKFNRLVNILDGFYKVNKNITSNSEEREIDEEVSDKKIIIFVSSQQFCDLLYSKLENFGYFPYTIHAGKPYQERVMNLEKFKTTTNSILLCTEVLSRGLNVPEVSLVIIYNAAKTFAQYVHTTGRTARGTHKGDAITLLLPDELAAAYILKRALRERELSSIDPQMVEDMKQMSERFESGMKEGKYKLSKGFGGKGLDNLDTKREEKQQEEKHKLDKIENDESTPSTSYKTTDNASSSSEVDSVTIPKLEFTIDRDKNIDSTISFTAIVNVNDLPQLVRWEATKNTTLMFIKHETGCSITNKGKYYPEGKGPTSNKDQPKLYLQIEGKEEKDVLLSIELLEQKVREGIKKVEYQSIKSTKY
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)
Length
862 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
95.319 kDa
Sequence
MSQLHTNSKEVHASSSNSQDDKLQKRRARLAAWNQKKASSEKSENNEDKKPKIESSKLQEWIKRRQQKSATPEVPSTEASQKPTSIKPILRARLSTSSSKQTQLVPKKRSIFDDDDEQDDAKTAKKDFRIPNEKKLPASTEEQESEDEEKVLERIRQAESGTSFLVESGFEQDLGADSGISGSEGDEEDDEEGQQRLLSEKLQKLTNKEKKLMALDYTQMEYTSVRKKFYTPPEELKDVPPEKVTALRTAMDGIKVRGSDCPMPIQKWAQLGLPSSIMTVLEEKLGYDTPSPIQSQALPAIMSGRDIIGVANTGSGKTLAFVIPLIRHIMDQPPLKSGDGPIGVILTPTRELALQIQKELVNFTQAVELSVCCCYGGSPIESQIADLKRGTEIIVGTPGRVIDLLAANGGRVTNLRRTTFLVLDEADRMFDMGFEPQVNKVLSQIRPDKQMVLFSATFPKKLESLARSFLVDPIEIVAGGISVVAPEITQRVVLIDDSGDISQKKLQALLKIVDEFSVEDPEGKILIFVDKQEAADDLMVRLLNNQISCIVIHGGKDQVDRKHAIKQFSDKNGLRVLIATSIAARGLDVRGLNLVINYDAPSHMEDYVHRVGRTGRAGATGTAVTLVLSSQEREIRDLVRAMKMSGKVDDIPAELQSIADKFLKKVKSGEEKFNSGFGGKGLENLQERRDNVREIEMQMYGDKVKETNGVSNSSAGRKALGTPEAAEIAGIKLPDFDIVEGRAPETSGPDRCKFHSRIEINDLPQKARWVVVNRDSLSKIIDATSTSITSKGQYYPPNSKLPKPTIKYGREIPPPPKLYLLVEGLTKSAVQEANKLLRQKMIEGVDVATEEDAKAPIGRYNV
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
855 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
95.774 kDa
Sequence
MEPNTPAIDPKKERLARWKQKKQQQDMLRQKSGASSKSSHDQAEDGDAARSTQPFEGLDKMAERRKRLELWKKKKKEQDEQKWKGDDAGQESATDIPVKGKAAPAEDAKAVPRGRKSRKGADPEKRQIWDDSDDELEAPKLKLFKPGSTIQTETPPDEDPEDTLDTYMNTIQEKNEVQLLAPREVFDQEDDETTAFDYNRTDNGTGSEFMRLAKLKAKKQLKPVIYSADELKPFIKNFYQEPEEISKLSEEEVADLRLSLDNVQVRGRDCPRPILKWSQLGLNSGIMNLLTRELEFTVPTPIQAQAIPAIMSGRDVIGISKTGSGKTVSFILPLLRQIKAQRPLGGDETGPLGLILSPTRELALQIHEEVTKFTSGDPSIRSLCCTGGSELKRQINDIKRGVEIVIATPGRFIDLLSLNSGNLINPKRIVFVVMDEADRLFDLGFEPQVNQIMKCIRPDKQCVLFSATFPNKLKSFASKILHDPVYITVNSKSLINENIEQKVEIFSNEEDKFKSLIHWLALTQQNLNDEKTIVFVSSQQICDILYNRLEANGFTTFAIHAGKIYTERAWNLKCFKETANGILICTEVLSRGLNVPEVSLVIIYNAAKTFAQYVHTTGRTARGSNKGTALTLLMNTELAASYILMKSMRDEELNKHHDATVSTLKQMSEKFNKGLKTGEYRLVKGFGGKGLDHLGKVYEEKHTEERNQLALEAGLAATEVSVSAPDGGLGDESTSVSIPKLDYTVKKRSNPDGTSTYFAHVQVNDLPQIVRWEATKYTTLSSIKHETGCSITNKGRYYPSGQGPQGPSDEPRLYLLVESATDQDISLAIDLLESKVRDGVRKSNMQEIRSNKYTI
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
849 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA.
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
96.359 kDa
Sequence
METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKEHQTSRNDIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKKISFDFSDDDDSEIGVSFRSKEHIQKAPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSAKFESGMKKGKFRLSKGFGGKGLENIKSKREEAQNKDLELKKNDKRSDDLEKKISNPREGHDSVSESSALIPRLNYELFKESTDGSIIFYAKVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFYPEGKEPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
849 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
96.412 kDa
Sequence
METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKENQTSRNDIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKKISFDFSDDDDSEIGVSFRSKEHIQKVPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSAKFESGMKKGKFRLSKGFGGKGLENIKSKREEAQNKDLELKKNDKRSDDLEKKINNPHEGHDSEPESSALIPRLNYELFKESTDGSIIFYAKVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFYPEGKEPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
816 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
92.283 kDa
Sequence
MTSIDKQKERLEKLARWKQKKSESKAVLNTQNVNTNSQSSNQNNVSDIENKLEKVKAWKKRKLEVKSDQQTPPATQSEINHTSSVRLEENIQGIKRKKRQKRVSNVFDEVKPINSTPTNDAQLSESDILEKVDLNTEDPLDSFFGNIETTEEFHFEVIDNKVNNDELLDEDNSKFDALQKEQKKLAKAKKNKNKKLLTPVNFRNIDLDPISKCLYNEPEEIKSYTEDEIADLRLDLDNIKIEGKDCPRPVTKWSQLGIPYDIIRFIKDVFSYKSLTPIQTQTIPAIMSGRDVIGISKTGSGKTISYLLPMIRHVKAQKKLRNGETGPIAVIFAPTRELAVQINEEVQKLISDLDISSICCTGGSDLKKQIDKLKTGVEIAIATPGRFIDLLSLNGGNLVSTLRISFVVMDEADRLFDFGFEPQIASVLRTVRPDRQCVLFSATFPSKVSNFASRFLDSPLQITVNAEGMVNERINQKFTICSDESDKFKELLSLLKVFNSETVDEKTIIFVSSQQICDIIEKRLTDYSEKLYSIHAGRPYNERRQNLELFKKTSNSILLCTEVMSRGLNVPEVSRVILYNSAKTFAQYVHSTGRTARGTREGTSISLLLPNELSSAYILNKAMRDKDFSECPVKEVKNLKQMAQKFEDGLKSGKYKLSTGLGGKGLENMDNSKETSNNDLDEQLKHQDNISISQEADLPDDFKFDTSVETVTNADGTIATVCKFVVNDLPQLVRWEMTKNTSISNMIRETGCSITLRGRYYPPSNVTNDNNTEPKLYLLIEATDDKAVRHCVDLLKDNARVGFMKATSESLRNTKY
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
PRP5
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
812 amino acids
Function
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Mass
91.154 kDa
Sequence
MDQTEKLRIRQEKLAKWKKQKLNNDVTASVSVDAKEERLKKLEAWKKKKKQQDELKQKDIKLTSIKSADRDRNKRRGQCSRKRPAFGGSDSESDDENSTSTLFKPRRNDTNTHVLTKDNSKDDLDDGNDALDEYIHKLIDKDSNTNRVRLIDNISEDEDANDSSSEKTISQEEAPVDSEILFKKKGRKKIKAIDYSKVLNLITLNKCLYREPNDLGLMSEKDVEELRLSLDNIKISGKDCPKPVTKWSQLGLSSEIMDLISNELQFVTLTPIQCQAIPAIMSGRDVIGISKTGSGKTVAFLLPLVRQIKAQPPLAPDETGPIGLILTPTRELAVQIQEEALKFCKGSGISSICCVGGSELKQQINELKRGVDIIVATPGRFIDLMTLNSGHLLSPTRISFVVMDEADRLFDLGFGPQVNQIMGCIRPDKQCVLFSATFPSKLKHFASRTLKNPIQITINSKSLINENIQQRVQIFDEEHVKFEFLLKRLSDRLALHRGEDEKTIIFVGSQQLCDLLYDELLLNGITTFPIHAGKPSAERLRNLQKFKETDNGILICTEVLSRGLNVPEVSLVIIYNAAKTIAQYVHTVGRTGRGTNNGVALSFVMVDELASAYILVKCMKENELSSVPMVVYQKLKEMNDEFSSGLKTGKYRLIQGFGGKGLDHLDELNEAKQSQEYTDYGVVENEEDVTEEESGATKMEYTRGKREEGHSTTYFAHININDLPQLARWEATKTETVSNIKQETGCNFESKGSFYPEGKGPKNDTDDPKLYLIVEGAEESDVTMALELLNTKVKEGIRKAAVKDIQSGKYRM
Protein
Pre-mRNA-processing ATP-dependent RNA helicase PRP5: PRP5

Gene
prp5
Protein
Pre-mRNA-splicing factor prp5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
473 amino acids
Function
Required for both cell cycle progression at G2/M and pre-mRNA splicing. Interacts genetically with the PRP4 kinase.
Similarity
Belongs to the WD repeat PRL1/PRL2 family.
Mass
52.418 kDa
Sequence
MTEAKNISDDTDVLSLTTNSLRTSKTLFGAEFGSVTSFDDTVAQNLKRTYKEHLEYGSVLGGTVGKRKNRHYEEDTIGSNALTVRADSENPSSQVITKFSDPNKKIAGQVSMQSLEKIKGVPEAAHRIAGESQASLVKRTLAEQIRPEWHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSDNIKHWKFPEGAFMGNFEGHNAIVNTLSINSDNVMFSGADNGSMCFWDWKSGHKYQELQSVVQPGSLDSEAGIFASSFDKTGLRLITCEADKSVKIYKQVDNATPETHPNLPWTPSNLRRRY
Protein
Pre-mRNA-splicing factor prp5: prp5