PRP4

Gene

prp4

Protein

Serine/threonine-protein kinase prp4

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

477 amino acids

Function

Has a role in pre-mRNA splicing and is essential for growth. Phosphorylates srp1.

Similarity

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.

Mass

55.222 kDa

Sequence

MSDDRFAEDEIIQQRRKRRLEILKKYQQTGNGHSDLSIPEKKLKEDVDQVSTTKPIEAVPKMKTNASKIEINKEGSNSNTKLDVTNSTTSDSPSIKSSVQIEDTEDDMFADSPSPSVKRQNTGKGISTLTRSFADMQDNWDDIEGYYKVVLMEELDSRYIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADREGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNVIHSDIKPDNMLVNEKRNILKICDLGSASDASENEITPYLVSRFYRAPEIILGFPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKMLKRSQFLNDHFDADFNFIQIDHDPITNQETRKPVKFSKPTKDIRSRLKEVPTSTDEEFIIRQELMDLLEKCLELNPEKRVPPEVALKHPFFIKK

Protein

Serine/threonine-protein kinase prp4: prp4

Gene

PRP4

Protein

U4/U6 small nuclear ribonucleoprotein PRP4

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

465 amino acids

Function

Involved in RNA splicing. Is required for the association of U4/U6 snRNP with U5 snRNP in an early step of spliceosome assembly.

Mass

52.442 kDa

Sequence

MSKYIALENLPVDLQHKGATQNESTADILKQLPHERLQAVLEKIPEEDLEVRRLLSILKKPEVVENEDVQQRRIRLAEILMVDEIDLENINNMENINGEEVDEEDDEDFFTPATSELIFARRFLINYSLERSRKRLQKEMERHQKFNTRQELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMISCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN

Protein

U4/U6 small nuclear ribonucleoprotein PRP4: PRP4

Gene

PRP4

Protein

Proline-rich protein 4

Organism

Arabidopsis thaliana

Length

448 amino acids

Similarity

Belongs to the plant proline-rich protein superfamily.

Mass

49.136 kDa

Sequence

MRILPEPRGSVPCLLLLVSVLLSATLSLARVVEVVGYAESKIKTPHAFSGLRVTIDCKVNKGHFVTKGSGNIDDKGKFGLNIPHDIVSDNGALKEECYAQLHSAAGTPCPAHDGLESTKIVFLSKSGDKHILGLKQNLKFSPEICVSKFFWPMPKLPPFKGFDHPFPLPPPLELPPFLKKPCPPKYSPPVEVPPPVPVYEPPPKKEIPPPVPVYDPPPKKEVPPPVPVYKPPPKVELPPPIPKKPCPPKPPKIEHPPPVPVYKPPPKIEKPPPVPVYKPPPKIEHPPPVPVHKLPKKPCPPKKVDPPPVPVHKPPTKKPCPPKKVDPPPVPVHKPPPKIVIPPPKIEHPPPVPVYKPPPKIEHPPIYIPPIVKKPCPPPVPIYKPPVVIPKKPCPPPVPVYKPPVVVIPKKPCPPLPQLPPLPKFPPLPPKYIHHPKFGKWPPLPPHP

Protein

Proline-rich protein 4: PRP4

Gene

PRP4

Protein

Placental prolactin-related protein 4

Organism

Bos taurus

Length

239 amino acids

Function

Placental prolactin-related proteins may play a specific role during gestation.

Similarity

Belongs to the somatotropin/prolactin family.

Mass

27.876 kDa

Sequence

MAPAPSFHGHQWTYNLVRGSCLLLLLVMSNLLLCQGILCPSLCPDGDDVCRASLIDLFVHASVLSTGMYNTSVKMFTDFDEQYAQGKEYFINVSDKCHTNSLHLPEDMQHNPTDEQKGLIMWILMLLYSWQRPLYQLVTDLRSMKEVSNTILSSARENVKKLKELQALIERPFSQVIFTARRKMYIARIYWFGLRSLLSSNEDRRHSAFYSLFFCLRRDTRKLDIYTKFVACRLIYKKC

Protein

Placental prolactin-related protein 4: PRP4