Prmt9

Protein arginine N-methyltransferase 9

846 amino acids

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA.

Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

94.22 kDa

MPNSRPRPRRGAGGGAGAAGRDRLVARSLQSAEHCLGDQDFGTAYAHYLLVLSLAPELKDDVKETFQYTLFKWAEELHALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFNDAKENFYRVANWLVERWHFIMLNDTRRNMVYNAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELACDVVAANKMENGIKLLHMKSLDIEIPKHIPERLSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPKTKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLPTNVKFQSPAYTSVDTEETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKPHSLNVPAIKEGVLDAIMVWFVLQLDDEYSLSTSPSEETCWEQAVYPVQALEDYCIQPGDRVTMEASCHDCYLRIQGISILHLEHEMEVMKGFTKSKDLLSLGNEAELCSALANLQTSRPEALEQTCMLEPTEIALLNNIPYHEGFKTAMRKVLSSLAPELLWQPMDTHCQYMEMNSGSGQSDAAPSTADPFYVLDVSEGFSLLPILAGTLGHVKPYSSVEKDQHCIALDLIAEANHFPKETLEFWLRHIEDEAAVLQRPKSDKLWSIIILDVIEPSGLIQQELMEKAAISRCLLQSGGKIFPQYVLMFGMLVESQTLVEESAVQGTEHTLGLNIAPFINQFQVPIRVCLDLSSLPCVPLSQPVELLRLDLMTPYLNTSNKEVKVRVCRSGRVTAVPFWFHLCLDDEVRLDTSGEASHWKQAAVVLDNPIQVQAGEELVLSVEHHKSNVSIAVKP

PRMT9

Protein arginine N-methyltransferase 9

845 amino acids

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).

Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

94.501 kDa

MSNSRPRSRRDAGGGAGAAGRDELVSRSLQSAEHCLGVQDFGTAYAHYLLVLSLAPELKHDVKETFQYTLFRWAEELDALSRIQDLLGCYEQALELFPDDEVICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFSDAKENFYRVANWLVERWHFIMLNDTKRNTIYNAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKTMYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRHHRVGIKDIAGIHLPTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLATKKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSPSEETCWEQAVYPVQDLADYWIKPGDHVMMEVSCQDCYLRIQSISVLGLECEMDVAKSFTQNKDLLSLGNEAELCSALANLQTSKPDAVEQTCILESTEIALLNNIPYHEGFKMAMSKVLSSLTPEKLYQTMDTHCQNEMSSGTGQSNTVQNILEPFYVLDVSEGFSVLPVIAGTLGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFWLRHVEDESAMLQRPKSDKLWSIIILDVIEPSGLIQQEIMEKAAISRCLLQSGGKIFPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLSKPVELLRLDLMTPYLNTSNREVKVYVCKSGRLTAIPFWYHMYLDEEIRLDTSSEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKSNVSITVKQ

prmt9

Protein arginine N-methyltransferase 9

827 amino acids

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).

Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

92.178 kDa

MAGQAASKRRLISRSLQSADICLQHQDYGTAYAHLLLVLTLAPEQKEALKEMFQYSLFKWAEELYALNRSQDLFNCYEQALELFPIDDVICNSMGEHLFRLGFRDEAAGYFYKALKLNPSSAEAKENFYRVANWLIERWHFIMLNDTKRNLMYRAAIQNAIQNGCKTVLDIGTGTGILSMFAKKAGAPFVYACELSKTMYELACEIVTANQMDGHIKLLHMKSHDIQIPEHIPERVSLVVTETVDAGLFGEGIVETLIHAWKNLLLQPKPKDGRVEAYGKVIPSSAVIYGMAVECPEIRRHYSVGVTEVAGIKLGDAVKFCSPIHSSHGPDDVTEPYTTEKMSRVPGGYKALSQPFQVMTVDFNSLQALEYIASGKSNRISVPVYQQGQFDCFITWFALQLDNEHSLSTEPSEETCWEQAVFPVQKLPDEGCLVNTGDTIVVDVSCPDCYLRLDLSTIVLSESSCDQTENMVMGNETDICDALANLHTTTNKGNMQELCILEPGEIALLNNAVYHESFMAAISKVIGSLELKESCSVVRNSQEQDVNFAQPVSEDRLHVLDVSEGFSILPLIAAKLGKVKAFSSVEKEQHRVALEKLSVINDLNNNESLEFCLSQLETDDGAAQKPKSDKMWSIIILDVIETCGLIRQDLLEKAAIARCLLEPGGKIFPHAVVMQGMLIESKTLLHEGSVQGNEPTLGFLIAPFINRFKVPAHVFLNLSTVPCIPLSEQFELLRLDLMNPCSNNQSSSVMRIKVNICRSGQVTAVTFWYHIHIDEAISLDTSSEASHWKQAAYVLETPTCVLEGEELLLEVQFQNSSMSMKLTRPLQ