PRAF1

Gene

PRAF1

Protein

PH, RCC1 and FYVE domains-containing protein 1

Organism

Arabidopsis thaliana

Length

1103 amino acids

Function

Binds to phosphatidic acid and to phosphoinositides such as PtdIns3P, PtdIns(3,4)P(2), PtdIns(3,4,5)P(3) and PtdIns(4,5)P(2). Catalyzes guanine nucleotide exchange on specific Rab proteins.

Mass

120.395 kDa

Sequence

MADLVTYSNADHNLEQALITLKKGTQLLKYGRKGKPKFYPFRLSSDEKSLIWISSSGEKRLKLASVSKIVPGQRTAVFQRYLRPEKDYLSFSLLYNGKKKSLDLICKDKVEAEIWIGGLKTLISTGQGGRSKIDGWSGGGLSVDASRELTSSSPSSSSASASRGHSSPGTPFNIDPITSPKSAEPEVPPTDSEKSHVALDNKNMQTKVSGSDGFRVSVSSAQSSSSHGSAADDSDALGDVYIWGEVICDNVVKVGIDKNASYLTTRTDVLVPKPLESNIVLDVHQIACGVRHAAFVTRQGEIFTWGEESGGRLGHGIGKDVFHPRLVESLTATSSVDFVACGEFHTCAVTLAGELYTWGDGTHNVGLLGHGSDISHWIPKRIAGSLEGLHVASVSCGPWHTALITSYGRLFTFGDGTFGVLGHGDKETVQYPREVESLSGLRTIAVSCGVWHTAAVVEIIVTQSNSSSVSSGKLFTWGDGDKNRLGHGDKDPRLKPTCVPALIDYNFHKIACGHSLTVGLTTSGQVFTMGSTVYGQLGNLQTDGKLPCLVEDKLASEFVEEISCGAYHVAALTSRNEVYTWGKGANGRLGHGDLEDRKVPTIVEALKDRHVKYIACGSNYTAAICLHKWVSGAEQSQCSTCRLAFGFTRKRHNCYNCGLVHCHSCSSKKAFRAALAPSAGRLYRVCDSCYVKLSKVSEINDTNRRNSAVPRLSGENRDRLDKSEIRLAKFGTSNMDLIKQLDSKAAKQGKKTDTFSLGRNSQLPSLLQLKDAVQSNIGDMRRATPKLAQAPSGISSRSVSPFSRRSSPPRSATPMPSTSGLYFPVGIADNMKKTNEILNQEIVKLRTQVDSLTQKCEFQEVELQNSVKKTQEALALAEEESAKSRAAKEAIKSLIAQLKDVAEKLPPGESVKLACLQNGLDQNGFHFPEENGFHPSRSESMTSSISSVAPFDFAFANASWSNLQSPKQTPRASERNSNAYPADPRLSSSGSVISERIEPFQFQNNSDNGSSQTGVNNTNQVEAEWIEQYEPGVYITLVALHDGTRDLRRVRFSRRRFGEHQAETWWSENREKVYEKYNVRVSEKSTASQTHRDRDEEEEDIPH

Protein

PH, RCC1 and FYVE domains-containing protein 1: PRAF1