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PPX2

Gene
ppx2
Protein
Exopolyphosphatase 2
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
319 amino acids
Function
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Prefers long-chain length polyphosphates as substrates.
Similarity
Belongs to the GppA/Ppx family.
Mass
33.664 kDa
Sequence
MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGVDATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVFFAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLGGGSTEIVLGEHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARRLVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSRVPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELRERAGIDQLTVSEHDILDGIALSLAG
Protein
Exopolyphosphatase 2: ppx2

Gene
ppx2
Protein
Exopolyphosphatase 2
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
319 amino acids
Function
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Prefers long-chain length polyphosphates as substrates (By similarity). Can also hydrolyze ATP and ADP substrates, but lacks GTPase activity. Cannot hydrolyze pppGpp to ppGpp (PubMed:22880033).
Similarity
Belongs to the GppA/Ppx family.
Mass
33.664 kDa
Sequence
MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGVDATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVFFAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLGGGSTEIVLGEHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARRLVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSRVPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELRERAGIDQLTVSEHDILDGIALSLAG
Protein
Exopolyphosphatase 2: ppx2

Gene
PPX2
Protein
Serine/threonine-protein phosphatase PP-X isozyme 2
Organism
Arabidopsis thaliana
Length
305 amino acids
Similarity
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
Mass
34.726 kDa
Sequence
MSDLDKQIEQLKRCEALKESEVKALCLKAMEILVEESNVQRVDAPVTICGDIHGQFYDMKELFKVGGDCPKTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVNVWRYCTDIFDYLSLSALVENKIFCVHGGLSPAIMTLDQIRAIDRKQEVPHDGAMCDLLWSDPEDIVDGWGLSPRGAGFLFGGSVVTSFNHSNNIDYICRAHQLVMEGYKWMFNSQIVTVWSAPNYCYRCGNVAAILELDENLNKEFRVFDAAPQESRGALAKKPAPDYFL
Protein
Serine/threonine-protein phosphatase PP-X isozyme 2: PPX2

Gene
Ppx2
Protein
Serine/threonine-protein phosphatase PP-X homolog 2
Organism
Paramecium tetraurelia
Length
303 amino acids
Similarity
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
Mass
34.643 kDa
Sequence
MSDIDQWIETLKNGENLKETDVKILCNKAKDILNNEDNVIRVEAPVTICGDIHGQFQDLMELFKVGGDVPETNYLFLGDFVDRGYNSVETFLLLLALKVRYPDQITLIRGNHESRQITQVYGFYDECLRKYSTLNVWKYCTEVFDYLALAAVVNDSIFCVHGGLSPYIKTIDEIRIINRKQEVPHEGVMCDLMWSDPDEIEGWSQSARGAGFVFGADVVKEFNRRNGISLICRAHQLAMEGFKLMFDNSLVTVWSAPNYCYRCGNVASILELDENLKKYYKLFEAAPTDRASNSKKTIADYFL
Protein
Serine/threonine-protein phosphatase PP-X homolog 2: Ppx2