ppr5

Pentatricopeptide repeat-containing protein 5, mitochondrial

1261 amino acids

Mitochondrial RNA-binding protein that acts as a general negative regulator of mitochondrial translation.

141.95 kDa

MVYTKAWFLQNIARQTLGKNVAVHRPPLKLGNMTNWIQQQQAQTNLSLSNTKAPGSLDERLFLTEDDIIFHDRSIQLGYFDPSLSERKQSPPGKSLHRFVDNLNPNSSHFSASLLPASLSSLCDSTCGDVDDEQQFNSLATSPLSTETQSEVSDPLLDTLTPNSLESSFASISLNSFTSANEFIQFLKRLASSKLSIHTFDLYKLVRNSPELLTLEAYNIVLQCMSTDDYFLSSSKNIQKIIKVYVDMLNSFISPNVTTFETVIFALCRRAKFVHQKIESLSKRTIYAHPSIAKEIQPELLDLQSEMPLQTAVFMFTSSLINHDLIYSPQFYAILIESVSLYGTQSQLDSLLECVPLGTIEANGHPDLLPALIRALGRAKRLNSCFQLLERYNLSDPTSDTSMTNVRSWEGLMEAYFDTDHHVEASALMKSFFRKADSNQVIPSSILDCFLRRLAQLGHYKESAEWLGMAIEKISTYKASPSTLSSILEAACLNNNDKFAIAFVRKYTLSRFSDCHAVLLRYLDLLARSGNVDLLHLHAYPVICSVSSHTNFTFSNVYKAFIENGKIDVALRLLRKHIDPKVSLGNNTAPSSNSVALQLSILNGFWEVLTEELQKDVHVLLSLVSTLENQVNFPQVDFTTPLLRHITGYLVSRRLEPELISPRVFGFLLEYAAFNVVQTEGTFTSKVILTDLLKCYSNGTYKASFKNVHVVLRSFTYLKEDEMLVASVRDDIVSEAVVGFSTDNNGQKILADISQVCYCLDDLECIDQSINSLVSKMLTSASPEQVDVNILFFQFGKLIETNKFLHPEVYPTLISVLSKNKRFDAVQRVFEHSKHLYRKISTKSLEKANWFMALILDAMILSSSFARQFKSSNLFCDNMKMLGYIPRASTFAHLINNSTRRGDTDDATTALNIFEETKRHNVKPSVFLYNAVLSKLGRARRTTECWKLFQEMKESGLLPTSVTYGTVINAACRIGDESLAEKLFAEMENQPNYQPRVAPYNTMIQFEVQTMFNREKALFYYNRLCATDIEPSSHTYKLLMDAYGTLKPVNVGSVKAVLELMERTDVPILSMHYAAYIHILGNVVSDVQAATSCYMNALAKHDAGEIQLDANLFQSQIESLIANDRIVEGIQIVSDMKRYNVSLNAYIVNALIKGFTKVGMISKARYYFDLLECEGMSGKEPSTYENMVRAYLSVNDGRKAMEIVEQLKRKRYPLPVVNRISSLVNSHMGQKPKRRSLNTSHSSLASLGNASTQHSINSSIN

PPR5

Pentatricopeptide repeat-containing protein PPR5, chloroplastic

499 amino acids

Involved in the biogenesis of the plastid translation machinery by promoting the splicing of group II introns in chloroplasts. Stabilizes the chloroplast trnG pre-RNA by directly binding to a group II intron, where it protects an endonuclease-sensitive site and stimulates splicing (PubMed:18591259). Binds specific sites within group II intron trnG pre-RNA. Binds with high affinity to the 5'-UTR of the chloroplastic petA mRNA (PubMed:18669444).

Belongs to the PPR family. P subfamily.

55.936 kDa

MLACPSTSSPWPQRQPPSPCPGGGGGATRHVALAARSKRRGAGPAAAEGVDEAAAEAAELVRSLLRRTAGGKERLVPVLDRHVRVVRTEHCFLLFEELGRRDAWLQCLDVFRWMQKQRWYVADNGIYSKLISVMGRKGQIRMAMWLFSQMRNSGCKPDTSVYNSLIGAHLHSRDKTKALAKALGYFEKMKCIERCQPTIVTYNILLRAFAQAGDTKQVDMLFKDLDESVVSPDVYTYNGVLDAYGKNGMIKEMESVLVRMKSTQCRPDVITFNILIDSYGRKQTFDKMEQVFKSLLRSKERPTHPTFNSMITNYGRARLREKAESVVEKMEELGFKPNYVTQECLIIMYAHCDCVSKARQVFDELVTSQTKVHLSSLNSMLEAYCMNGLHTEADRLLDTALQQCVVPNGSTYKLLYKAYTKANDKLLVQKLLKRMNKQGIVPNKKFFLDALEAFGTSDRKPRTSPGINSASKPSTDSAGDSETATSDKPEVSVWHVAAT