PPP6R2

Serine/threonine-protein phosphatase 6 regulatory subunit 2

966 amino acids

Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.

Belongs to the SAPS family.

104.942 kDa

MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVSLITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDRLGGDESLLSLLYDFLDHEPPLNPLLASFFSKTIGNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEALEPDPLLTALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGTEGLVDSFSQGLERSYAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERTEASGSESRVEPPHENGNRSLETPQPAASLPDNTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISEVIRGLPADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQAFSDYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCSDRIQPFDDDEDEDIWEDSDTRCAARVMARPRFGAPHASESCSKNGPERGGQDGKASLEAHRDAPGAGAPPAPGKKEAPPVEGDSEGAMWTAVFDEPANSTPTAPGVVRDVGSSVWAAGTSAPEEKGWAKFTDFQPFCCSESGPRCSSPVDTECSHAEGSRSQGPEKASQASYFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSHSEDGDQKAASAMDAVSRGPGREAPPLPTVARTEEAVGRVGCADSRLLSPACPAPKEVTAAPAVAVPPEATVAITTALSKAGPAIPTPAVSSALAVAVPLGPIMAVTAAPAMVATLGTVTKDGKTDAPPEGAALNGPV

Ppp6r2

Serine/threonine-protein phosphatase 6 regulatory subunit 2

923 amino acids

Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.

Belongs to the SAPS family.

100.46 kDa

MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVNLITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDRLGEDESLLNLLYDFLDQEPPLNPLLASFFSKTIGNLIARKTEQVIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKIIQRLVALIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETVEPDPLLITLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGTEGLVDSFSQGLERSHSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPGINQELCRLNTMDLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREEQAEASGSDGKVEPLQGSGDGNGKLETTPSITSPPENTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISEVIRGLPADCRGRWESFVEETLMETNRRNTVDLAFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADEDSPSAALFEACCSDRIQPFDDDEEEDIWEDDETRCAARVMARARFGAPHVSDNYSKNALEHGGQDRKTGSAVARNVPGLAAPSSPTQKEGPRSESDSAGTTWTAVFDEPVNPLSATPGAARDVGSSAWAAGPSVVEEKGWAKFTDFQPFCCSETGPRCSSPVDMDHSNAEGGQSPGPEKTFGPTSPCAWNVCVTRKAPLVASDSSSSGGSDSEDDEKAAGAVEAVCTGHTGKVSPPPRTAEAAVGRAECPDSTVLAPACPAPSEVTISPAVATIAPSKAGSPTATIVVSSSVAAAVPPGPIVAVTTAAPAIVATLGTMTKDRKADALPEGAALNGPV