Protein
Protection of telomeres protein 1a
Organism
Arabidopsis thaliana
Function
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for positive telomere length regulation. Binds specifically the telomerase RNA template component TER1. Does not bind single-stranded telomeric DNA. Not required to recruit telomerase to telomeres, but stimulates TER1 RNP repeat addition processivity (PubMed:25329641).
Similarity
Belongs to the telombin family.
Sequence
MAKKRESPKLIKIKDAIKLINQQVSLIGIVLEQREPKQCRNNDWICTLRIIDDTYPSPGLTVNVFSKTLEQLPQIKNHDDMILFTRIKMQTFDSGERVNAACSRWVSSFALFEGVDFVCYQCSTNFHEEEALYKSAMDDLRKVFAGCSQVIKAMQSISYRTKPCSEVFSFLREIKIGKRFDLVCRILHADEDTSAVFVWDGTDAPPASILAKRSEEDKAFSSLSVHTLLSRDVLLSFPTVGTILRVHLSSHLFYRVKPGDWVKLYHLLCEVDRGSWVIKVTSSTKVHHLAQDDRLVEKIMRIYDKRLSSKLGHISFWCFPSPPGLTETDDNCAPFVTLMDIITFPKVTCKYRCIVRVVAAYPWQVEDFCSDENRRHHQVLLTLEDSTATLEAFLCNKDAEYFWGLGFQDTETLRKKRNWLLGIRESSNFVAPRNPPWIECCILSYYTNKADPWNTRLYRIFGTRLLH