Protein
DNA-directed RNA polymerases I and III subunit rpac1
Organism
Dictyostelium discoideum
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
Similarity
Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
Sequence
MVNKSTTNGVSDPNLENKRTKVTLTNSGVENARGTYYSGAYTSVGYDNSFNLNRFKENFKINILSESANELVFEMIGIDAPIANALRRIMISEIPTMAIEKVYIINNTSILQDEVLAHRLGMIPIKVDPRKFNFKLPNKEYTAEDTLIFQLKVKCEKDSVTGKIINETALSKHLIWVPTQDQEEMFPNEEDRPRPMEDDIPIMKLRPGQVIDIQCYCEKNIGREHIKWSPVCTASYRLQPVISVDKSIKGDKANQLLEKCPKKVFDIEDSGQVVAARPLDCTMCRECIRDPEFEQNVKIERVRDHFIFSIESTGALKSREIFQEAIKIFIEKCNIVEESINKLVN