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PNOC

Gene
Pnoc
Protein
Prepronociceptin
Organism
Mus musculus
Length
187 amino acids
Function
Orphanin FQ2: Has potent analgesic activity.
Similarity
Belongs to the opioid neuropeptide precursor family.
Mass
20.884 kDa
Sequence
MKILFCDVLLLSLLSSVFSSCPRDCLTCQEKLHPAPDSFNLKTCILQCEEKVFPRPLWTVCTKVMASGSGQLSPADPELVSAALYQPKASEMQHLKRMPRVRSLVQVRDAEPGADAEPGADAEPGADDAEEVEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV

Gene
Pnoc
Protein
Prepronociceptin
Organism
Rattus norvegicus
Length
181 amino acids
Function
Orphanin FQ2: Has potent analgesic activity.
Similarity
Belongs to the opioid neuropeptide precursor family.
Mass
20.479 kDa
Sequence
MKILFCDVLLLSLLSSVFSSCPEDCLTCQERLHPAPGSFNLKLCILQCEEKVFPRPLWTLCTKAMASDSEQLSPADPELTSAALYQSKASEMQHLKRMPRVRSVVQARDAEPEADAEPVADEADEVEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV

Gene
PNOC
Protein
Prepronociceptin
Organism
Bos taurus
Length
176 amino acids
Function
Orphanin FQ2: Has potent analgesic activity.
Similarity
Belongs to the opioid neuropeptide precursor family.
Mass
20.256 kDa
Sequence
MKILFCDLLLLSLFSSVSSSCQKDCLVCREKLRPTLDSFSLEMCILECEEKAFTSPLWTPCTKVMARGSWQLSPADPDHVAAALDQPRASEMQHLKRMPRVRSLFQRQKRTEPGLEEVGEIEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNA

Gene
PNOC
Protein
Prepronociceptin
Organism
Homo sapiens
Length
176 amino acids
Function
Orphanin FQ2: Has potent analgesic activity.
Similarity
Belongs to the opioid neuropeptide precursor family.
Mass
20.295 kDa
Sequence
MKVLLCDLLLLSLFSSVFSSCQRDCLTCQEKLHPALDSFDLEVCILECEEKVFPSPLWTPCTKVMARSSWQLSPAAPEHVAAALYQPRASEMQHLRRMPRVRSLFQEQEEPEPGMEEAGEMEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV

Gene
PNOC
Protein
Nociceptin
Organism
Sus scrofa
Length
17 amino acids
Function
Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. When administered intracerebroventricularly into mice, this peptide induces hyperalgesia and decreases locomotor activity.
Similarity
Belongs to the opioid neuropeptide precursor family.
Mass
1.809 kDa
Sequence
FGGFTGARKSARKLANQ