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PM20D1

Gene
PM20D1
Protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Organism
Gallus gallus
Length
517 amino acids
Function
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Similarity
Belongs to the peptidase M20A family.
Mass
57.162 kDa
Sequence
MAGGCGRRRVVVCAVALGLSAAVLALTAVVLLRAYVLRSPAIPRLWARRGSTAAFSASERRELKEALRGAVRIPTVSLSSEDFNTTAMAEFGDYIRKAFPAVFSSKFIQHEIIGEYSHLFTVQGSDSEMMPYMLLAHMDVVPAPPEGWDFPPFSAAEHEGFIYGRGTLDNKNSAIGILQALEFLLRRNYRPRRSFYVGIGHDEEVFGQKGALKIAALLESRGVKLSFLLDEGSAILDGIIAGVKKPVALIAVTEKGLMTLNFTVEKEPGHSSFPPKETSIGILATAVSRLEQNPMRSLFGRGPELMTMEHLASEFNFPLNLIMSNLWLFSPIVSRVLAWKPSTNALIRTTTAVTMFNAGIKFNVIPPSARATVNFRIHSGEKAKEVLETVRNTVADDRVKIDVIEALDPLPISPWDDQTFGVHVFQRTILDTFPNVDSVVPGTCIGNTDSRHFTNVTNAIYRFNPVLLKSDDLPRIHGLNERISVESYEKQVEFLFQLIKNCDVDKLPEPHANSHEL

Gene
pm20d1
Protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Organism
Xenopus tropicalis
Length
512 amino acids
Function
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Similarity
Belongs to the peptidase M20A family.
Mass
56.71 kDa
Sequence
MAVSRWKAVGSTLLAAFLVGLVVLIAVLLIRTYTLPTAVRKWNRNESLITELAEKERKQLVEALKGAIRIPTVSFSEEEQNTTALREFGEYIQKVFPQVFSSSLIQHEVLGGYSHLFKVQGSDHNLLPYMLLAHIDVVPAPPESWEVPPFSGEERDGYIYGRGTLDDKNCVIGILQSLEFLLKRGHKPRRSFYIGLGHDEEISGHKGAQKIVEKLQSQGVKLAFVLDEGLAVLDGVIQGISQPVALVGTTEKGSVTLDLTVNRLPGHSSMPPSETSIGILAAAVSRLEQNMMPNMFGNGPEQDMFEHLSTKFDFPLNIIMANLWLFSPILSRILELSPSTNAIVRTTTALTIFKAGIKSNVIPPTATATVNFRLHPAQTVQEVLDIVQNTIKDERVELSVLNSFDPLPVSPNDMSLGYHILQRTIHDVFSGPPVAPGVCVGNTDSRHFVNLTNSIYRFSPVVLKKEDVDRIHGLNERISKEAIELLVQFYIQLIQNSDTDNIPPPHLDTHEL

Gene
PM20D1
Protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Organism
Bos taurus
Length
503 amino acids
Function
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Similarity
Belongs to the peptidase M20A family.
Mass
55.785 kDa
Sequence
MARPSVCLLASLSALLLGIAAVSRSKGLRGTESQREPRIPSQFSQEQRIAMKEALKGAIQIPTVSFSPKELNTTALAEFGEYIRKVFPTVFHTSFIRHEVVGNYSHLFTIKGSDPSMQPYILLAHIDVVPAPDKGWDVPPFSGLERDGFIYGRGTLDNKNYLMAILQALELLLIRNYIPRRSFFIALGHDEEISGINGAQKISALLQARGVQLAFVVDEGSFILDGFIPYLKKPFAMVSVSEKGAINLMLQVNTTTGHSSAPPKETSIGILAAAVSRLEQTPMPNMFGSGPLMTAVEQLANEFPFPTNIVLNNLWLFRPLVSRLMERNYITNSLVRTTTALTMFNAGVKVNVIPPVAEAIINFRLHPAQTVQEVLKLAKDIVADDRIQFHVLDAFDPLPISPSDDQALGYQLLRQTIHSVFPEVNIVAPGTCIGNTDSRHYLNLTTGIYRFNPIYLQPQDFSSIHGINEKISVQAYETQVKFVFEFIQNGDTDEETVPHLHEL

Gene
Pm20d1
Protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Organism
Mus musculus
Length
503 amino acids
Function
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Similarity
Belongs to the peptidase M20A family.
Mass
55.663 kDa
Sequence
MAELLASLPAWAAVLLLFFATVSGSTGPRSRENRGASRIPSQFSEEERVAIKEALKGAIQIPTVSFSHEESNTTALAEFGEYIRKAFPTVFHSSLVQHEVVAKYSHLFTIQGSDPSLQPYMLMAHIDVVPAPEEGWEVPPFSGLERNGFIYGRGALDNKNSVMAILHALELLLIRNYSPKRSFFIALGHDEEVSGEKGAQKISALLQARGVQLAFLVDEGSFILEGFIPNLEKPVAMISVTEKGALDLMLQVNMTPGHSSAPPKETSIGILSAAVSRLEQTPMPNMFGGGPLKKTMKLLANEFSFPINIVLRNLWLFHPIVSRIMERNPITNALVRTTTALTMFNAGIKVNVIPPLAQATINCRIHPSQTVHEVLELVKNTVADDRVQLHVLRSFEPLPISPSDDQAMGYQLLQETIRSVFPEVDIVVPGICIANTDTRHYANITNGMYRFNPLPLNPQDFSGVHGINEKVSVQNYQNQVKFIFEFIQNADTYKEPVPHLHEL

Gene
PM20D1
Protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Organism
Homo sapiens
Length
502 amino acids
Function
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Similarity
Belongs to the peptidase M20A family.
Mass
55.741 kDa
Sequence
MAQRCVCVLALVAMLLLVFPTVSRSMGPRSGEHQRASRIPSQFSKEERVAMKEALKGAIQIPTVTFSSEKSNTTALAEFGKYIHKVFPTVVSTSFIQHEVVEEYSHLFTIQGSDPSLQPYLLMAHFDVVPAPEEGWEVPPFSGLERDGIIYGRGTLDDKNSVMALLQALELLLIRKYIPRRSFFISLGHDEESSGTGAQRISALLQSRGVQLAFIVDEGGFILDDFIPNFKKPIALIAVSEKGSMNLMLQVNMTSGHSSAPPKETSIGILAAAVSRLEQTPMPIIFGSGTVVTVLQQLANEFPFPVNIILSNPWLFEPLISRFMERNPLTNAIIRTTTALTIFKAGVKFNVIPPVAQATVNFRIHPGQTVQEVLELTKNIVADNRVQFHVLSAFDPLPVSPSDDKALGYQLLRQTVQSVFPEVNITAPVTSIGNTDSRFFTNLTTGIYRFYPIYIQPEDFKRIHGVNEKISVQAYETQVKFIFELIQNADTDQEPVSHLHKL