Protein
RxLR effector protein PITG_02860
Organism
Phytophthora infestans (strain T30-4)
Function
Effector that promotes P.infestans virulence and suppresses pattern-triggered immunity (PTI) (PubMed:26966171, PubMed:30049706). Interacts with the host ubiquitin E3 ligase NRL1 and enhances the association between NRL1 and SWAP70 to promote proteasome-mediated degradation of SWAP70, which results in the suppression of immunity (PubMed:26966171, PubMed:30049706).
Similarity
Belongs to the RxLR effector family.
Sequence
MRLAFLLLAVSHFICGNALPTNVKSSPVVSPGLIQSFDNAQKPVVMSRKLLRTDERLSEANEERTKLSELFRLDDDEVAAIKELSSMFSAFLQKKSQAFDVYDEIFRSGYPIDTAARISNLYTKYLKDPQAFRGP