Function
May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3.
Sequence
MAAPSPGPREILAPSPEAGRRAAASSSGHRGLLWRLRDKQCRLGLFEIGPGHELHQVMCLMQAGLWAATQVSMDHPPTGLPTEEDFSEVLTQVHEGFELGTLAGPVFARLRRSLGLAEEDYQAALGPSRPYLQFLSTSKSKASFFLSHDQRFFLKTLRSREVQALLAHLPRYVHHLQRHPHSLLARVLGVHSLRVARGKKKYFIVMQSVFYPAGRISERYDIKGCEVSRWVEPAPEGSVLVLVLKDLNFQGKTINLGPQRSWFLRQMELDTAFLRELNVLDYSLLMAFQRLHEDERGPGSSLIFRTARSIRGAQSAEESGAQNRRLLPDAPNALHIVDGPEHRYFLGLVDLTTVYGLRKRLEQLWKTLRYPGRTFSTVSPACYARRLCQWVEAHTE