Protein
Phosphatidylinositol 4-kinase PIK1alpha
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Function
Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate.
Similarity
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Sequence
MSADITETPNKQLLEQIRSPSFSLFNCIYELKNHTDSIGIQHELVKKLYSFPYEDLQFFIPQFVQLLVTYDSESMALEEFIITYSSRYPHFSLIVFWNLQAYIFELKNEPESRSFQAVRNLITKIQNIMFNADQQTVKAPEFRENFLPALVLCGAVASSVLLPSFKSYCLPMIKAQGKQQKSLVFKLVNFQKSLTKNLTLKNQRMSADIPKGSHSDDETATSSSIKPSLSRSASVPRRNTKKTSLSFSSDESEAYTTDDDDNKTSIELEKDFYKIDLDGLSKEKSANFLEPEENLNVNTAIKSKKRLSTLTSKVMTQPWNGIDGYNVNSQSLPDLSKAEGRDLIPFISSTESETSLLYHNNSISNDLQKNIPRQQKFSPGFDNVYLTKLLQVNYAKNETQFIMALQNISIRLSQVPKEARLSALRAELSIINDTLLPSEIDIPQLLPITSNRNKKYHKILKLNVNEASVLNSAERVPFLLFIEYLSDEIDFNPTTEYNQRIIARKKMNGATSMTVKKINSFSEVADGNFEKENKIKSSTPETVSNIIYNENTEEADLSEMPLDRKTTVSSDSFSPEMLVTPSITEQSKLSNFPSLNTKEVSTKVLADQMRIAAVMLQQLDSSGKANSEQSFLIKNRIVESMIALQDQFDSFDFEKLSQLQSDEPSAGERKLENDFKLGEDWNTKKQRIKKSSAYGHLKNWDLCSVIAKNGDDLPQEAFACQLISMISNIWKKNNIPVWTKRMKILITSANTGLVETITNAMSIHSIKKSFTEHSIKSGENSKGKIFTLLDYFHSVFGSPNSTSFRTAQQNFAKSLAAYSIICYVLQIKDRHNGNIMVDGDGHIIHIDFGFLLSNSPGSVGFEAAPFKLTVEYVELLGGVDSEIYSQFVYLCKQCFKSLRDNSEEIIEIVELMQKDSTLPCFNNGENTSVLLKQRLQLQLNDEDTDQFVENFLIGKSLGSMYTRLYDQFQMITQGIYS