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PIGX

Gene
PIGX
Protein
Phosphatidylinositol-glycan biosynthesis class X protein
Organism
Homo sapiens
Length
258 amino acids
Function
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
Similarity
Belongs to the PIGX family.
Mass
28.788 kDa
Sequence
MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRDLLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPNYLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFPILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITILCSTLILVAVFKYGHFSL

Gene
Pigx
Protein
Phosphatidylinositol-glycan biosynthesis class X protein
Organism
Mus musculus
Length
254 amino acids
Function
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
Similarity
Belongs to the PIGX family.
Mass
28.644 kDa
Sequence
MAAGAVAWLLLWAAWLVGRLAADFSDAPFSAGKGVRATCSEIILRQEFLKDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPPGLFVDPYELASLRERNLTEAVMLSESFNIEAPNYLSNESAVLIYARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMYCDQEFPILKCWAQSEVAAPCALKSEEICQWKSMQYKSILKNLTVQVPVGLTIHTSLVCSVTLLITILCSTLILLAVFKYGHFSL

Gene
Pigx
Protein
Phosphatidylinositol-glycan biosynthesis class X protein
Organism
Rattus norvegicus
Length
252 amino acids
Function
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM.
Similarity
Belongs to the PIGX family.
Mass
28.423 kDa
Sequence
MAASALAWLLLWAAGLVGRLAADISDARFSDGVRATCSEIILRQEFLKDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNITEAVMVSESFNLEAPNYLSTESAVLIYARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPILKCWAQSEVAAPCSLKSEEICQWKNMQYKSILKNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAVFKYGHFSL