Protein
Phosphatidylinositol-glycan biosynthesis class W protein
Organism
Rattus norvegicus
Function
Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (PubMed:14517336).
Similarity
Belongs to the PIGW family.
Sequence
MSQKQLKEAFVSNLSGTSVLEVTQGLCFPAFCILCRGLLIIFSQHLCSFLHTWTTQFFMDFVVLIVPLVITLTVLSSFILLENLTVILCGAWLLYQIYHRRTCYAKVPVQKVFASFLKISLESEYNPAITCYRVINSVFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFIFGAAMVCPEVRRKYTEGSRFNHLRKSLYSVWPLVFLGMGRLVIIKSIGYQEHSTEYGVHWNFFFTIIVVKLITSLLLIIFPLNKSWIVAISITVLYQLALDFTPLKGIILYGTDGRGTRVGLLNANREGIISTLGYVAIYMAGVQTGFYVFKRRAQVRDWIKATCWVFSVAVGFFISLNIVQVNVEAVSRRMANLAFCLWVVASSLMLLSCLLLSGIVLSFAKFLIKGALVPCSWKLIQSATTNRQSESLIVEAEKNKPSFCLITALNRNQLFFFLLSNVATGLINLTVDTLHTGAFWTLAVLSIYMFANCLVIYVLDLQGKTIKFW