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PIFO

Gene
Pifo
Protein
Protein pitchfork
Organism
Mus musculus
Length
207 amino acids
Function
During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner.
Mass
23.434 kDa
Sequence
MNTEEIPVAPPLRGVTPALQWKVNNYSFGTRQARKLFPHYHPPTWLGNLYLPLRGMPHTGPGCYAAATDWNGLAYNLSKVPTSTKGYAIGARTAVRFKPISKDVTPYPGMYQKVDTLSEKHKKSFAPFNILMPRFRSAAKGDSYPGPGTYNPEMKSVPKVTWPMKFGSPDWSQVPCLEKRTLKAELSADKDFRKHRSRVAYFSLYYQ

Gene
PIFO
Protein
Protein pitchfork
Organism
Bos taurus
Length
192 amino acids
Function
During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner (By similarity).
Mass
22.173 kDa
Sequence
MCFSQAETLVNYSFGTCQHRKIFPHFFPSDLLGNKFLPIRGVPHRGPGCYIAEESKDLAYSLAKIPTSIKGYGFGARTAVRFKPKNKDVTPYPGMYQTVNLQEQTHKPNFAPFNTLSPRFRTYSKDPCYPGPGTYKLEKKEPQKVTWPMKFGSPDWSQVPCLQKRTLKTELSTDKDFRKHRNRLAYLSLYYN

Gene
PIFO
Protein
Protein pitchfork
Organism
Homo sapiens
Length
191 amino acids
Function
During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner.
Mass
21.973 kDa
Sequence
MCFSRADAADNYPFGTCQQRKLFPHFHPPNLIGNKFVPLRGSPHRGPGCYFSDGYGLAYDLSKIPTSIKGYTLGARTAVRFKPIQKEMTPHAGRYQKVSPQQEKHKQNFAPFNVLVPRFKNYPKDTYYPSPGAYNPEKKPPPKIAWPMKFGSPDWAQVPCLQKRTLKAELSTDKDFRKHRNRVAYLSLYYN