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PICST_53561

Gene
PICST_53561
Protein
Succinate dehydrogenase assembly factor 2, mitochondrial
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
149 amino acids
Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
Similarity
Belongs to the SDHAF2 family.
Mass
17.729 kDa
Sequence
MLRNRITSRRSISSSVSALANYGKPQNPAIDTTVKMRIQPIKREGETMEIKRARLIYQSRKRGILESDLLLSRFAKKYLNEFTEAELDEYDRLLDEPDWDIYYWATKNYDVTPLPDKWKDSKILKMLQEDAKNDDREILRMPELDLEQK