PH1618

Gene

PH1618

Protein

UDP-N-acetyl-D-mannosamine dehydrogenase

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

Length

418 amino acids

Function

Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).

Similarity

Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

Mass

46.134 kDa

Sequence

MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLSLGKLKVTDRVEDLKGSNVFIICVQTPLSGDDPDLSYLERAIRTVAEVMDRGALVIIESTIPPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAANLAEKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVYEAIELANTHPRVKIHTPGIGVGGHCLPKDPYLLLSNAKEDFGLIRIARRINERMPAFAAGLLFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEIIRNSVKEVRTYDPYVRGTHDSLEKVVEGADAIVIATDHPEFKSVNWESIGKSMRHKIIIDGRNIIKEPPVGFIFRGIGRGDV

Protein

UDP-N-acetyl-D-mannosamine dehydrogenase: PH1618