Protein
Digeranylgeranylglyceryl phosphate synthase
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
Sequence
MEPKAFVEIMRPHNCILAGIVGILGSLVAYEGIPPVQKLILIFLVVYFGCSAGNTINDYFDVEIDKINRPNRPIPRGAITRKAAFYYGVLQYFIGLIIALLLGWSAFLFALGAYFLTFVYAWKLKPLPFIGNVTVALLTAATPIYGAVGVGRIDLAGYLAICAFLVNVSREIMKDIEDFEGDKRLGARTLPIMIGKKKSGIIASIFGFLTIISSFLPVKVGIGLGYLPIIIVDIMIAKASIDVLVNPEKAGKGQKILKFATFIAVISFLLGALTREV