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PGF

Gene
PGF
Protein
Placenta growth factor
Organism
Homo sapiens
Length
221 amino acids
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Similarity
Belongs to the PDGF/VEGF growth factor family.
Mass
24.789 kDa
Sequence
MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRHSPGRQSPDMPGDFRADAPSFLPPRRSLPMLFRMEWGCALTGSQSAVWPSSPVPEEIPRMHPGRNGKKQQRKPLREKMKPERCGDAVPRR

Gene
Pgf
Protein
Placenta growth factor
Organism
Mus musculus
Length
158 amino acids
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).
Similarity
Belongs to the PDGF/VEGF growth factor family.
Mass
17.876 kDa
Sequence
MLVMKLFTCFLQVLAGLAVHSQGALSAGNNSTEVEVVPFNEVWGRSYCRPMEKLVYILDEYPDEVSHIFSPSCVLLSRCSGCCGDEGLHCVPIKTANITMQILKIPPNRDPHFYVEMTFSQDVLCECRPILETTKAERRKTKGKRKRSRNSQTEEPHP

Gene
Pgf
Protein
Placenta growth factor
Organism
Rattus norvegicus
Length
158 amino acids
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).
Similarity
Belongs to the PDGF/VEGF growth factor family.
Mass
17.681 kDa
Sequence
MLAMKLFTCFLQVLAGLAVHSQGALSAGNNSTEMEVVPFNEVWGRSYCRPMEKLVYIADEHPNEVSHIFSPSCVLLSRCSGCCGDEGLHCVALKTANITMQILKIPPNRDPHSYVEMTFSQDVLCECRPILETTKAERRKTKGKRKQSKTPQTEEPHL

Gene
PGF
Protein
Placenta growth factor
Organism
Bos taurus
Length
149 amino acids
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).
Similarity
Belongs to the PDGF/VEGF growth factor family.
Mass
17.094 kDa
Sequence
MPTVRLFTCFLQLLTGLVLPAVPTTQWALSPGNISSEVEVVPFQQVWSRSYCRPVERLVDIVSEYPSEMEHLFSPSCVSLMRCTGCCSDESMHCVPLETANVTMQLMKYRSLDQPFFVEMSFSQHVRCECKPLWEKMKQTRCGDTISQR