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PGA7

Gene
PGA7
Protein
Predicted GPI-anchored protein 7
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
219 amino acids
Function
GPI-linked hyphal surface heme-binding protein involved in heme-iron utilization. Heme transfer can occur bi-directionally between PGA7 and RBT5, supporting a model in which they cooperate in a heme-aquisition system. The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms. Required for biofilm formation.
Similarity
Belongs to the RBT5 family.
Mass
22.42 kDa
Sequence
MHFIFYLILLVSAADYGNFGTYPKVPKTASINGFADPIYDLLPDCAKECVKFSTSNTPCPYWDTGCFCVMPQWAGLVGQCVAQKCKGEDVASARFLATSLCSVVGANTWMMPASISSMLSTAAGDAKEVTTIEGKTAKSWVTAPGSAAGSVVSETGSASETGSSESAQSTTTGSSSTGSSSTDSSSSSSSSPSSSANFAVLQTGGIGSVILGFMMYLLV