Protein
Cofilin/actin-depolymerizing factor homolog 2
Organism
Plasmodium falciparum (isolate 3D7)
Function
Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments. Essential for erythrocytic schizogony (By similarity).
Similarity
Belongs to the actin-binding proteins ADF family.
Sequence
MVSGVKVSDECVYEFNKLKIKHIHKYIIYRIENYEEVIVDFLEQDNSLKSYKDIIIDIRNNLKTTECRYIIADMPIPTPEGVLRNRIYFIFWSPDLAKSKEKMLYASSKEYLVRKINGIFKSLEITCDLEDFEDELRTIILNT