Protein
PPi-type phosphoenolpyruvate carboxykinase 1
Organism
Entamoeba histolytica
Function
Inorganic pyrophosphate (PPi)-dependent phosphoenolpyruvate carboxykinase, which regulates the carbon flow of the central metabolism by fixing CO(2) to phosphoenolpyruvate to produce oxaloacetate. Can also produce pyruvate and diphosphate from phosphoenolpyruvate and phosphate.
Similarity
Belongs to the PPi-type phosphoenolpyruvate carboxykinase family.
Sequence
MFNQEKGTDYPILNIQELEALADLKLSAMGKEYPKHDKSDAIDVVAPLVDIIAEGDQESTAPIDARLQTFLNSYFAECGEEVPKIPDNTFILDREGLGRVLSFPPHKQEFFCETMKSYKIKQGVLHNPAKDKRTTVGVFHICQSDVPVPADKIECPKIAFLRMLKAAFYGAPDDHLIIPYTAECKEPTRSWVSLYMRPVVVPGVKGVKGFEHEKATEMHFFVPGNMVSCLDFVESVFGNAGNPRLSKNDAALDPLGWTGHSGMAILAPHLTRMTKKECGLPHISQATERQKRERMCWEKEDELYNDGKTFKMYCRDASGVICTIIADNYFGYCKKEVKTQISYSANLYGFAEEEHAGGAVTRPSYDLGEACKAVQYAEGYKFSEMVEKNKHSIIVKEEGYAVDKKYPEGIIYVPEDSVFTIEDASIKFNHNGKEESILLTPKVNYVLPNGYTIILHDTMTSRRWTLRGILPQYTLCHKPCTVSGGGKSEISKNISDAIFEGKMFVNNKEEEFKAVQKVFDHDFSRRYADGEIKSAHILDPNVTLGTVVKMLTPSSFFTEEHNEFVAAIPPMIVELALTIKSLYREEWKGDWQSRITVDKINGKEGHELKYRKMPLPSQYLRVGFERDETTWRVFQLRKDFFPAAKLQMEDDITASVIVPTKLLKTPINTNGKKACKIVKNCELRLFQRPDDAVFRGYDKQTEYDFSIPGHFISNYQPMTREEAKDFTKDVVRLYQYTEPMRKCLQDFVAGKDEAKYIVSSSHTRLVQDGDKLVGSKNPRYLQRRPDMLDPEYTYMTFKAIQLFRKISDEEPLYTPVDAVLSGRRNNPPQVAKNGMKLRPLSVFAPLHYFELPELLMECITSMTGASPSMFGAGSEGALTKGPFNSLPAVVDLNNYLLGMICCGYSGFVSSASYCGPHYKVAHDISLLIPEIWSRMRRYEQEPKYLIEHGYLEPCPDVTYNGKTYSGKRLGYRITKDFTVHYFSSIFSVPNSVMPEDFLKPELQDLAIYADSYEYIEQTDKGIAMNYVKDGTVEGACPPLKALIYIMANGEYNGMTRESKEFREMFDAKTILNSEWYKERLVTRQKLEVAKLNKDLAYLNKTIAEKPRLAETLNKQIAAVKEELQYVSSEEYLIDIDGSIGTDPYPYKCMKH