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PCBER1

Gene
PCBER1
Protein
Phenylcoumaran benzylic ether reductase 1
Organism
Arabidopsis thaliana
Length
308 amino acids
Function
Oxidoreductase involved in lignan biosynthesis. Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC). Plays an important role in the biosynthesis of secondary metabolites. In addition to the 8-5'-linked neolignan DDC, can reduce the 8-8'-linked lignans, pinoresinol, and lariciresinol, but with lower activities.
Similarity
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Mass
34.072 kDa
Sequence
MTSKSKILFIGGTGYIGKYIVEASARSGHPTLVLVRNSTLTSPSRSSTIENFKNLGVQFLLGDLDDHTSLVNSIKQADVVISTVGHSLLGHQYKIISAIKEAGNVKRFFPSEFGNDVDRVFTVEPAKSAYATKAKIRRTIEAEGIPYTYVSCNFFAGYFLPTLAQPGATSAPRDKVIVLGDGNPKAVFNKEEDIGTYTINAVDDPRTLNKILYIRPPMNTYSFNDLVSLWENKIGKTLERIYVPEEQLLKQIIESSPPLNVMLSLCHCVFVKGGHTSFEIEPSFGVEASELYPDVKYTTVDEILNQYV