Protein
Pterin-4-alpha-carbinolamine dehydratase
Function
Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity).
Similarity
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Sequence
MAGKAHRLNAEEREQLLPNLRAVGWNEVEGRDAIFKEFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECTGLSERDINLASFIEQVAASLS