PAFAH2

Platelet-activating factor acetylhydrolase 2, cytoplasmic

392 amino acids

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.

Belongs to the serine esterase family.

43.865 kDa

MGVNQSVSFPPVTGPHLVGCGDVMEGQSLQGSFFRLFYPCQEAEETSEQPLWIPRYEYCAGLAEYLKFNKRWGGLLFNLGVGSCRLPVSWNGPFKTKDSGYPLIIFSHGMGAFRTVYSAFCMELASRGFVVAVPEHRDGSAAATCFCKQTPEENQPDNEALKEEWIPHRQIEEGEKEFYVRNYQVHQRVSECVRVLKILQEVTAGQAVLNILPGGLDLMTLKGGIDVSRVAVMGHSFGGATAILALAKEMQFRCAVALDAWMFPLEHDFYPTARGPIFFINAEKFQTVETVNLMKKICDQHHQSRIITVLGSVHRSLTDFVFVAGNWISKFFSSHTRGSLDPYEGQETVVRAMLAFLQKHLDLKEDYDQWNNFIEGIGPSLTPGAPHHLSSL

PAFAH2

Platelet-activating factor acetylhydrolase 2, cytoplasmic

392 amino acids

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.

Belongs to the serine esterase family.

44.036 kDa

MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCTGLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHVRNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGATAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQHEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKHLDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL

Pafah2

Platelet-activating factor acetylhydrolase 2, cytoplasmic

390 amino acids

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme (By similarity).

Belongs to the serine esterase family.

43.562 kDa

MGAGQSVCFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCQASEKCEQPLWIPRYEYSMGLADYLQYNKRWVGLLFNVGIGSCRLPVSWNGPFKAKESGYPLIILSHGLGGFRASYSAFCMELASRGFVVAAVEHRDQSAAATYFCKPTSQESSPAESLEEEWLPFRRIKEGEKEFHVRNPQVHQRVKECVRVLRILQDASAGKTVVNVFPGGLDLMTLKGSIDRNRVAVMGHSFGGATAVLALTQEVQFRCAIALDAWMFPLERDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAFVTGNLIAKFFSSNSRGTLDPYESQEVMVRAILAFLQKHLDLKEDYDQWSSFIEGVGPSLIQGAPHYLSSL

Pafah2

Platelet-activating factor acetylhydrolase 2, cytoplasmic

390 amino acids

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Acts as a PAF-acetylhydrolase in the absence of lipid acceptor molecules.

Belongs to the serine esterase family.

43.492 kDa

MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADYLQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGFVVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVRVLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIALDAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAFVTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAPHYLSSL