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PA4608

Gene
PA4608
Protein
Cyclic diguanosine monophosphate-binding protein PA4608
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
125 amino acids
Function
Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
Mass
14.573 kDa
Sequence
MSDQHDERRRFHRIAFDADSEILQGERRWEVLLHDVSLHGILVGQPQDWNGDPQRPFEARLYLGLDVLIRMEISLAWARDGLLGFECQHIDLDSISHLRRLVELNLGDEELLERELALLVSAHDD