Protein
Protein N-terminal glutamine amidohydrolase
Organism
Oryza sativa subsp. indica
Function
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
Similarity
Belongs to the NTAQ1 family.
Sequence
MADDRVAGGATPPPPPPPPPLDASAFTHTPYYCEENVHLLCKELIRSGISDPAGTDLYAVFISNEEKKVPLWYQKASHSGDGFVLWDYHVICIQSRRKNGEVLDLVWDLDSSLPFPCSFIQYVSDAIRPLSFGNSTYRRLFRVIHAPVFLRSFASDRSHMKDHAGNWIQLPPKYESIVAEDGTTNNLNEYITMSMDDVKDLESMADDVYSSKHGVVINETILPEFFSRLPG